T
Tae-Ho Hwang
Publications - 1
Citations - 1100
Tae-Ho Hwang is an academic researcher. The author has contributed to research in topics: Wnt signaling pathway & LRP5. The author has an hindex of 1, co-authored 1 publications receiving 1068 citations.
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Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
Masaki Kato,Millan S. Patel,Regis Levasseur,Ivan Borisovich Lobov,Benny Hung-Junn Chang,Donald A. Glass,Christine Hartmann,Lan Li,Tae-Ho Hwang,Cory Brayton,Richard A. Lang,Gerard Karsenty,Lawrence Chan +12 more
TL;DR: It is shown that mice with a targeted disruption of Lrp5 develop a low bone mass phenotype, and it is demonstrated that this phenotype becomes evident postnatally, and that it is secondary to decreased osteoblast proliferation and function in a Cbfa1-independent manner.