C
Cory Brayton
Researcher at Johns Hopkins University School of Medicine
Publications - 95
Citations - 6316
Cory Brayton is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Medicine & In vivo. The author has an hindex of 27, co-authored 86 publications receiving 5642 citations. Previous affiliations of Cory Brayton include Baylor College of Medicine & University of York.
Papers
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Journal ArticleDOI
p53 mutant mice that display early ageing-associated phenotypes
Stuart D. Tyner,Sundaresan Venkatachalam,Jene Choi,Stephen N. Jones,Nader Ghebranious,Herbert Igelmann,Xiongbin Lu,Gabrielle Soron,Benjamin A. Cooper,Cory Brayton,Sanghee Park,Timothy C. Thompson,Gerard Karsenty,Allan Bradley,Lawrence A. Donehower +14 more
TL;DR: It is suggested that p53 has a role in regulating organismal ageing by generating mice with a deletion mutation in the first six exons of the p53 gene that express a truncated RNA capable of encoding a carboxy-terminal p53 fragment.
Journal ArticleDOI
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
Masaki Kato,Millan S. Patel,Regis Levasseur,Ivan Borisovich Lobov,Benny Hung-Junn Chang,Donald A. Glass,Christine Hartmann,Lan Li,Tae-Ho Hwang,Cory Brayton,Richard A. Lang,Gerard Karsenty,Lawrence Chan +12 more
TL;DR: It is shown that mice with a targeted disruption of Lrp5 develop a low bone mass phenotype, and it is demonstrated that this phenotype becomes evident postnatally, and that it is secondary to decreased osteoblast proliferation and function in a Cbfa1-independent manner.
Journal ArticleDOI
Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice.
Scott C. Kogan,Jerrold M. Ward,Miriam R. Anver,Jules J. Berman,Cory Brayton,Robert D. Cardiff,John S. Carter,Sherri de Coronado,James R. Downing,Torgny N. Fredrickson,Diana C. Haines,Alan W. Harris,Nancy L. Harris,Hiroshi Hiai,Elaine S. Jaffe,Ian C. M. MacLennan,Pier Paolo Pandolfi,Paul K. Pattengale,Archibald S. Perkins,R. Mark Simpson,Mark S. Tuttle,Joanne F. Wong,Herbert C. Morse +22 more
TL;DR: This classification will be of particular value to investigators seeking to develop, use, and communicate about mouse models of human hematopoietic neoplasms in order to diagnose lesions as well-defined entities according to accepted criteria.
Book
The laboratory mouse
TL;DR: This chapter discusses the development of Phenotyping Terminology and Tests, and some of the techniques used to develop and evaluate these techniques.
Journal Article
Dimethyl sulfoxide (DMSO): a review.
TL;DR: The scientific literature is reviewed with particular attention to mechanisms underlying DMSO's reported therapeutic and toxic effects, and its potential value in specific, approved and unapproved veterinary applications is discussed.