T
Taha M. A. Eldebss
Researcher at Cairo University
Publications - 29
Citations - 677
Taha M. A. Eldebss is an academic researcher from Cairo University. The author has contributed to research in topics: Pyrazole & Benzimidazole. The author has an hindex of 12, co-authored 26 publications receiving 556 citations.
Papers
More filters
Journal ArticleDOI
Synthesis, spectral characterization, solution equilibria, in vitro antibacterial and cytotoxic activities of Cu(II), Ni(II), Mn(II), Co(II) and Zn(II) complexes with Schiff base derived from 5-bromosalicylaldehyde and 2-aminomethylthiophene
TL;DR: Protonation constants of (ATS) ligand and stability constants of its Cu2+, Co2+, Mn2+ and Ni2+ complexes were determined by potentiometric titration method in 50% (v/v) DMSO-water solution at ionic strength of 0.1 M NaNO3.
Journal ArticleDOI
Synthesis of some new pyrazole-based 1,3-thiazoles and 1,3,4-thiadiazoles as anticancer agents.
TL;DR: N-(4-(Pyrazol-4-yl)thiazol-2-yl)-N'-phenylthiourea derivative 2 was synthesized and then treated with variety of hydrazonoyl chlorides under basic condition at reflux to afford the corresponding 2-( 4-(pyrazol)-1,3,4-thiadiazole derivatives 6, 10a-e and 17a- e.
Journal ArticleDOI
Synthesis and antiviral activity of some new bis-1,3-thiazole derivatives.
TL;DR: The goal of the work was achieved in discovering a very active compound 10a as anti HCV agent (EC50 0.56 μM) in structure elucidation of the products.
Journal ArticleDOI
Design, synthesis and structure-activity relationship study of novel pyrazole-based heterocycles as potential antitumor agents.
Ahmad M. Farag,Korany A. Ali,Taha M. A. Eldebss,Abdelrahman S. Mayhoub,Abd El-Galil E. Amr,Naglaa A. Abdel-Hafez,Mohamed M. Abdulla +6 more
TL;DR: All tested compounds showed anti-estrogenic properties equipotent or superior to the reference drug, letrozole.
Journal ArticleDOI
Synthesis and Structure‐Activity Relationship Studies of Pyrazole‐based Heterocycles as Antitumor Agents
Ahmad M. Farag,Abdelrahman S. Mayhoub,Taha M. A. Eldebss,Abd El-Galil E. Amr,Korany A. Ali,Naglaa A. Abdel-Hafez,Mohamed M. Abdulla +6 more
TL;DR: Three compounds synthesized starting from ethyl 4‐cyano‐1,5‐diphenylpyrazoles attached to different heterocyclic ring systems at position 3 revealed the highest cytotoxic activity and the oral LD50 values revealed that most of the tested compounds are relatively nontoxic.