T
Tai Yuan Chen
Researcher at Academia Sinica
Publications - 5
Citations - 146
Tai Yuan Chen is an academic researcher from Academia Sinica. The author has contributed to research in topics: Systematic evolution of ligands by exponential enrichment & Aptamer. The author has an hindex of 4, co-authored 5 publications receiving 133 citations. Previous affiliations of Tai Yuan Chen include Memorial Hospital of South Bend & National Taiwan Ocean University.
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Breast Tumor Microenvironment: Proteomics Highlights the Treatments Targeting Secretome
TL;DR: A newly designed technique integrating a capillary ultrafiltration probe with mass spectrometry was demonstrated to dynamically sample and identify in vivo and pure secretome from the tumor microenvironment, which may facilitate the development of novel drugs specifically targeting secretome.
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Neural cell protective compounds isolated from Phoenix hanceana var. formosana.
Yi Pei Lin,Tai Yuan Chen,Hsiang-Wen Tseng,Mei Hsien Lee,Mei Hsien Lee,Shui-Tein Chen,Shui-Tein Chen +6 more
TL;DR: Isovitexin, luteolin-7-O-beta-d-glucopyranoside (4), and (+)-catechin (8) protected PC12 cells from 6-OHDA-induced apoptotic neurotoxicity and showed significant neuroprotective activity in cell viability, anti-apoptosis, and cellular ROS scavenging assays.
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Rapid detection of natriuretic peptides by a microfluidic LabChip analyzer with DNA aptamers: Application of natriuretic peptide detection
Ming-Cheng Lin,Jiraporn Nawarak,Tai Yuan Chen,Hsien-Yu Tsai,Jung-Feng Hsieh,Supachok Sinchaikul,Shui-Tein Chen +6 more
TL;DR: By combining the fluorescent-labeled aptamers with fast protein lab-on-chip analysis, this work could achieve quantification of BNP concentrations with high speed, sensitivity, and specificity.
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Chemical and biological evaluation of nephrocizin in protecting nerve growth factor-differentiated PC12 cells by 6-hydroxydopamine-induced neurotoxicity
Yi Pei Lin,Tai Yuan Chen,Hsiang-Wen Tseng,Mei Hsien Lee,Mei Hsien Lee,Shui-Tein Chen,Shui-Tein Chen +6 more
TL;DR: The results demonstrate the first neuroprotective mechanism of nephrocizin against 6-OHDA-, H₂O₁- or p-quinone-induced cytotoxicity in PC12 cells via chemical and biological studies.
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Functional regulation and proteomic characterization of human natural killer cells through recombinant human granulocyte-colony stimulating factor treatment
Yu-Jen Chen,Yu-Jen Chen,Chih-Chia Yu,Shui-Tein Chen,Shui-Tein Chen,Tai Yuan Chen,Hui-Fen Liao +6 more
TL;DR: It is concluded that rhG‐ CSF may impair NK‐mediated cytotoxicity accompanied by alterations in protein expression profile distinct from that of rhGM‐CSF.