T
Takafumi Sai
Researcher at University of Tokyo
Publications - 9
Citations - 153
Takafumi Sai is an academic researcher from University of Tokyo. The author has contributed to research in topics: Granulosa cell & MPTP. The author has an hindex of 6, co-authored 9 publications receiving 125 citations. Previous affiliations of Takafumi Sai include Toray Industries.
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Journal ArticleDOI
Expression and Function of Apoptosis Initiator FOXO3 in Granulosa Cells During Follicular Atresia in Pig Ovaries
Fuko Matsuda,Naoko Inoue,Akihisa Maeda,Yuan Cheng,Takafumi Sai,Hiroshi Gonda,Yasufumi Goto,Kazuhiro Sakamaki,Noboru Manabe +8 more
TL;DR: Forkhead box O3 is expressed in porcine ovarian follicles and induces apoptosis in granulosa cells, suggesting that it is a candidate for the initiator of follicular atresia.
Journal ArticleDOI
Bid and Bax are involved in granulosa cell apoptosis during follicular atresia in porcine ovaries.
Takafumi Sai,Yasufumi Goto,Ryousuke Yoshioka,Akihisa Maeda,Fuko Matsuda,Miki Sugimoto,Kannika Wongpanit,Hua-Zi Jin,Junyou Li,Noboru Manabe +9 more
TL;DR: Results indicate that Bid and Bax appear to be signal transduction factors ingranulosa cells during follicular atresia and appear to play proapoptotic roles and confirm that the porcine granulosa cell is a mitochondrion-dependent type II apoptotic cell.
Journal ArticleDOI
Regulation of granulosa cell apoptosis by death ligand–receptor signaling
Fuko Matsuda-Minehata,Akihisa Maeda,Yuan Cheng,Takafumi Sai,Hiroshi Gonda,Yasufumi Goto,Noboru Manabe +6 more
TL;DR: An overview of granulosa cell apoptosis regulated by death ligand-receptor signaling is provided and the roles of death ligands and receptors, caspases, apoptotic protease-activating factor 1, TNFR-associated factor 2 and cellular FLICE-like inhibitory protein in granulosity cells are discussed.
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A review of pulmonary toxicity studies of nanocellulose.
Takafumi Sai,Katsuhide Fujita +1 more
TL;DR: This review summarizes the progress of in vivo experiments on the effects of NC on the respiratory system by inhalation and will provide new insights into NC toxicity studies by comparing the results of fibrous nanomaterials.
Journal ArticleDOI
Acute toxicity of MPTP and MPP+ in the brain of embryo and newborn mice
TL;DR: The present results may indicate that MPTP and MPP(+) pass through the placenta and blood-brain barrier (BBB) and that a different mechanism may be involved in MPTP- orMPP(+)-induced toxicity in the SVZ and in the nigrostriatal system of embryonic and newborn mice.