N
Noboru Manabe
Researcher at University of Tokyo
Publications - 179
Citations - 4181
Noboru Manabe is an academic researcher from University of Tokyo. The author has contributed to research in topics: Follicular atresia & Granulosa cell. The author has an hindex of 33, co-authored 178 publications receiving 3805 citations. Previous affiliations of Noboru Manabe include Kyoto University & Osaka International University.
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Journal ArticleDOI
Follicular Growth and Atresia in Mammalian Ovaries: Regulation by Survival and Death of Granulosa Cells
TL;DR: The factors that govern follicular growth and atresia, with a special focus on their regulation by granulosa cells, are discussed, in which hormones, growth factors and cytokines, death ligand-receptor system and B cell lymphoma/leukemia 2 (BCL2) family members are further discussed.
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Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia.
Noboru Manabe,Yasufumi Goto,Yasufumi Goto,Fuko Matsuda-Minehata,Naoko Inoue,Akihisa Maeda,Akihisa Maeda,Kazuhiro Sakamaki,Takashi Miyano +8 more
TL;DR: It is shown that the porcine granulosa cell is a type II apoptotic cell, which has the mitochondrion-dependent apoptosis-signaling pathway, and the cell death receptor-mediated apoptosis signaling pathway ingranulosa cells has been suggested to be as follows.
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The Regulation of Ovarian Granulosa Cell Death by Pro- and Anti-apoptotic Molecules
TL;DR: The endocrinological regulatory mechanisms involved in follicular development and atresia have been characterized to a large extent, but the precise temporal and molecular mechanisms involvedIn the regulation of these events have remained largely unknown.
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Involvement of fas antigen in ovarian follicular atresia and luteolysis
Kazuhiro Sakamaki,Hisahiro Yoshida,Yoshiko Nishimura,Shin-Ichi Nishikawa,Noboru Manabe,Shin Yonehara +5 more
TL;DR: It is reported that Fas protein is expressed on granulosa and luteal cells but not on oocytes in the ovary, suggesting that Fas plays an important role in follicular atresia and lutenolysis in the ovarian physiology of adult mice.
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Cellular Retinol-Binding Protein-1 Expression and Modulation during In Vivo and In Vitro Myofibroblastic Differentiation of Rat Hepatic Stellate Cells and Portal Fibroblasts
Kozue Uchio,Beatriz Tuchweber,Noboru Manabe,Giulio Gabbiani,Jean Rosenbaum,Alexis Desmoulière +5 more
TL;DR: In normal liver, CRBP-1 expression was different among fibroblastic cells, a finding that adds to the concept of heterogeneity of liver fibrogenic cells, and data suggest a correlation between CRBP -1 expression and myofibro Blastic differentiation.