T
Takao Matsuo
Researcher at Takeda Pharmaceutical Company
Publications - 31
Citations - 614
Takao Matsuo is an academic researcher from Takeda Pharmaceutical Company. The author has contributed to research in topics: Insulin & Hyperinsulinemia. The author has an hindex of 12, co-authored 31 publications receiving 607 citations. Previous affiliations of Takao Matsuo include Osaka University.
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A New Genetically Obese-Hyperglycemic Rat (Wistar Fatty)
TL;DR: The survey showed that Wistar fatty rats (fa/fa), a congenic strain of WKY, developed obesity and obesity-related features, such as hyperinsulinemia and hyperlipemia, in the same manner as Zucker fatty rats.
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Dietary ascorbic acid depresses plasma and low density lipoprotein lipid peroxidation in genetically scorbutic rats.
TL;DR: Examination of the effects of dietary ascorbic acid on plasma lipoprotein and liver lipid peroxide concentrations in ODS od/od rats with a genetic defect in the ability to synthesize ascorBic acid found that increasing ascor bic acid concentration in the diet inhibited the development of these ascorinic acid deficiency symptoms in a dose-dependent manner.
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An α-glucosidase inhibitor, AO-128, retards carbohydrate absorption in rats and humans
TL;DR: Results indicated that AO-128 retards the absorption of carbohydrate and reduces post-prandial hyperglycemia.
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PVN-lesioned obese rats maintain ambulatory activity and its circadian rhythm
Koh Tokunaga,Yuji Matsuzawa,Shigenori Fujioka,T Kobatake,Y Keno,Hiroyuki Odaka,Takao Matsuo,Seiichiro Tarui +7 more
TL;DR: It is demonstrated that the PVN-lesioned obese rats show clear differences in physiological behavior from the VMH-lesions, in which circadian rhythm was abolished.
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Antiobesity and antidiabetic actions of a new potent disaccharidase inhibitor in genetically obese-diabetic mice, kkay
TL;DR: Findings indicate that AO-128 may be useful for treating human obesity and diabetes.