T
Takeshi Kurata
Researcher at Centers for Disease Control and Prevention
Publications - 39
Citations - 2487
Takeshi Kurata is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Vaccination & Virus. The author has an hindex of 27, co-authored 39 publications receiving 2444 citations. Previous affiliations of Takeshi Kurata include University of Tokyo.
Papers
More filters
Journal ArticleDOI
Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit.
TL;DR: The results suggest that either CT or CTB could be used as a potent adjuvant to induce protective secretory antibodies by nasal vaccination against pathogens impinging on respiratory mucosa.
Journal ArticleDOI
Isolation and characterization of mouse nasal-associated lymphoid tissue
Hideki Asanuma,Amy Hodson Thompson,Takuya Iwasaki,Yuko Sato,Yuji Inaba,Chikara Aizawa,Takeshi Kurata,Shinichi Tamura +7 more
TL;DR: The results suggest that this method for isolation of mouse nasal-associated lymphoid tissue (NALT) can be successfully used for investigating cellular dynamics of mucosal immunology in the upper respiratory tract.
Journal Article
Cross-protection against influenza virus infection afforded by trivalent inactivated vaccines inoculated intranasally with cholera toxin B subunit.
Shin-ichi Tamura,Y. Ito,Hideki Asanuma,Yoshihiro Hirabayashi,Yutaka Suzuki,Takashi Nagamine,Chikara Aizawa,Takeshi Kurata +7 more
TL;DR: In mice immunized intranasally with a nasal site-restricted volume of inactivated vaccines together with cholera toxin B subunit (CTB) as an adjuvant, nasal inoculation of trivalent vaccines with CTB provides cross-protection against a broader range of viruses than does the current parenteral vaccination.
Journal ArticleDOI
Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine.
Shinichi Tamura,Aya Yamanaka,Miyuki Shimohara,Toshio Tomita,Katsuhiro Komase,Yusuke Tsuda,Yujiro Suzuki,Takashi Nagamine,Kazuyoshi Kawahara,Hirofumi Danbara,Chikara Aizawa,Akira Oya,Takeshi Kurata +12 more
TL;DR: Cholera toxin B subunit (CTB) and Escherichia coli heat-labile toxin (LTB) were examined for the adjuvant effect on antibody (Ab) response against influenza inactivated HA (haemagglutinin) vaccine in Balb/c mice as discussed by the authors.
Journal ArticleDOI
Cross-protection against influenza A virus infection by passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules.
Shin-ichi Tamura,H. Funato,Yoshihiro Hirabayashi,Yasuhiro Suzuki,Takashi Nagamine,Chikara Aizawa,Takeshi Kurata +6 more
TL;DR: It is demonstrated that IgA antibodies to influenza A virus HA by themselves play a pivotal role in defence not only against homologous virus infection, but also against heterologous drift virus infection at the respiratory mucosa, the portal of entry for the viruses.