T
Takeshi Matsui
Researcher at Nara Institute of Science and Technology
Publications - 5
Citations - 2426
Takeshi Matsui is an academic researcher from Nara Institute of Science and Technology. The author has contributed to research in topics: MAP kinase kinase kinase & Serine/threonine-specific protein kinase. The author has an hindex of 4, co-authored 4 publications receiving 2371 citations.
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Journal ArticleDOI
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
Takeshi Matsui,Mutsuki Amano,Takaharu Yamamoto,Kazuyasu Chihara,Masato Nakafuku,Mikako Ito,Takeshi Nakano,K. Okawa,A. Iwamatsu,Kozo Kaibuchi +9 more
TL;DR: P purified a Rho‐interacting protein with a molecular mass of approximately 164 kDa (p164) from bovine brain that bound to GTPgammaS (a non‐hydrolyzable GTP analog) and is likely to be a putative target serine/threonine kinase for Rho and serves as a mediator of the RHo‐dependent signaling pathway.
Journal ArticleDOI
Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association
Takeshi Matsui,Masato Maeda,Yoshinori Doi,Shigenobu Yonemura,Mutsuki Amano,Kozo Kaibuchi,Sachiko Tsukita,S Tsukita +7 more
TL;DR: Observations indicate that the Rho-kinase–dependent phosphorylation interferes with the intramolecular and/ or intermolecular head-to-tail association of ERM proteins, which is an important mechanism of regulation of their activity as actin filament/plasma membrane cross-linkers.
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Identification of a putative target for Rho as the serine-threonine kinase protein kinase N
Mutsuki Amano,Hideyuki Mukai,Yoshitaka Ono,Kazuyasu Chihara,Takeshi Matsui,Yuko Hamajima,Katsuya Okawa,Akihiro Iwamatsu,Kozo Kaibuchi +8 more
TL;DR: Activation of Rho may be linked directly to a serine-threonine kinase pathway, and this phosphorylation was blocked by treatment of cells with botulinum C3 exoenzyme.
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A novel GTPase-activating protein for R-Ras
TL;DR: P98, an R-Ras-interacting protein purified from bovine brain cytosol by glutathione S-transferase (GST)-R-RAS affinity column chromatography, shows a high degree of sequence similarity to the entire sequence of Gap1, one of the GTPase-activating proteins (GAP) for Ha-Ra.
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Energy-efficient production of vaccine protein against porcine edema disease from transgenic lettuce (Lactuca sativa L.)
TL;DR: In this paper , the authors investigated methods to minimize the input light energy per target protein to reduce production costs and found that Stx2eB was produced 1.4 times more efficiently per unit area time using a high plant density (228.5 plants m −2 s −1 , 24 h, and white LED lamps.