Tarik F. Massoud

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TL;DR: The present review summarizes the chemistry, pharmacokinetics, biodistribution, metabolism, and toxicity of bulk gold in humans based on decades of clinical observation and experiments in which gold was used to treat patients with rheumatoid arthritis.

TL;DR: Six parameters of AVM angioarchitecture were correlated with a clinical presentation of hemorrhage and three (feeding by perforators, number of aneurysms, and presence of intranidal aneurYSms) were well displayed by superselective angiogram.

TL;DR: Results show that multitarget antagonization of endogenous miRNAs could be an efficient strategy for targeting metastasis and antiapoptosis in the treatment of metastatic cancer.

TL;DR: Red light-emitting reporter systems based on bioluminescence resonance energy transfer (BRET) that allow for assaying PPIs both in cell culture and deep tissues of small animals are described and used for ratiometric imaging and validate their applicability for studying PPIs in mice in the context of rapamycin-induced FK506 binding protein 12 (FKBP 12)-FKBP12Rapamycin binding domain (FRB) association.