Cristina Zavaleta

TL;DR: It is shown that single-walled carbon nanotubes conjugated with cyclic Arg-Gly-Asp (RGD) peptides can be used as a contrast agent for photoacoustic imaging of tumours and intravenous administration showed eight times greater photoac acoustic signal in the tumour than mice injected with non-targeted nanot tubes.

TL;DR: It is shown that a unique triple-modality magnetic resonance imaging–photoacoustic imaging–Raman imaging nanoparticle approach can accurately help delineate the margins of brain tumors in living mice both preoperatively and intraoperatively.

TL;DR: The ability of Raman spectroscopy to separate the spectral fingerprints of up to 10 different types of surface enhanced Raman scattering (SERS) nanoparticles in a living mouse after s.c. injection shows great potential for multiplexed imaging in living subjects in cases in which several targeted SERS probes could offer better detection of multiple biomarkers associated with a specific disease.

TL;DR: Noninvasive deep-tissue molecular images in a living subject with the use of Raman spectroscopy are presented and the imaging modality reported here holds significant potential as a strategy for biomedical imaging of living subjects.

TL;DR: The present review summarizes the chemistry, pharmacokinetics, biodistribution, metabolism, and toxicity of bulk gold in humans based on decades of clinical observation and experiments in which gold was used to treat patients with rheumatoid arthritis.