Tarshi Droma

TL;DR: This small sample of healthy Tibetans with lifelong residence had resting pulmonary arterial pressures that were normal by sea-level standards and exhibited minimal hypoxic pulmonary vasoconstriction, both at rest and during exercise, consistent with remarkable cardiac performance and high-altitude adaptation.

TL;DR: It is suggested that mtDNA mutations are unlikely to play a major role in the adaptation of Tibetans to high altitudes and is supportive of previous genetic evidence that Tibetans, although located in southern Asia, share common ancestral origins with northern Mongoloid populations.

TL;DR: It is concluded that reduced uterine blood flow and altered pelvic blood flow distribution during pregnancy at high altitude likely contributed to the altitude-associated reduction in infant birth weight.

TL;DR: It is suggested that those living at high altitude the longest have the least altitude‐associated intrauterine growth restriction and have lower levels of prenatal and postnatal mortality than those living there for a shorter period of time.

TL;DR: It is concluded that lifelong Tibetan residents of high altitude neither hypoventilated nor exhibited blunted hypoxic ventilatory responses compared with acclimatized Han newcomers, suggesting that the effects of lifelong high-altitude residence on ventilation and ventilatories response to hypoxia differ in Tibetan compared with other high-ALTitude populations.