John T. Reeves

TL;DR: Mortality was most closely associated with right ventricular hemodynamic function and can be characterized by means of an equation using three variables: mean pulmonary artery pressure, mean right atrial pressure, and cardiac index.

TL;DR: This is an international consensus statement of an ad hoc committee formed by the International Society for Mountain Medicine and represents the committee's interpretation of the current knowledge with regard to the most common chronic and subacute high altitude diseases.

TL;DR: It is concluded that circulating mesenchymal precursors of a monocyte/macrophage lineage, including fibrocytes, are essential contributors to hypoxia-induced pulmonary vascular remodeling.

TL;DR: The findings suggest that although glycogenolysis may be accentuated at low work loads, it may not be maximally activated at exhaustion, and with increasing altitude, blood lactate was progressively reduced at maximal exercise, whereas at any absolute and relative submaximal work load, blood latate was higher.

TL;DR: Mediation of thehypoxic response by this type of excitation-contraction coupling is consistent with the idea that hypoxia has a direct depolarizing effect on the vascular smooth muscle and provides a unifying explanation for inhibition of the hypoxic mechanism by various agents that have depressant or stabilizing actions on membranes in addition to other pharmacological effects.