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Tatiana S. Frolova

Researcher at Novosibirsk State University

Publications -  10
Citations -  96

Tatiana S. Frolova is an academic researcher from Novosibirsk State University. The author has contributed to research in topics: Ursolic acid & Cytotoxicity. The author has an hindex of 3, co-authored 10 publications receiving 34 citations. Previous affiliations of Tatiana S. Frolova include Russian Academy of Sciences.

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Synthesis and cytotoxicity of hybrids of 1,3,4- or 1,2,5-oxadiazoles tethered from ursane and lupane core with 1,2,3-triazole.

TL;DR: In this paper, 1,3-cycloaddition reactions of azole-derived azides with alkyne esters connected to positions C-3 and C-28 of triterpene core were tested for cytotoxicity.
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Synthesis of cytotoxic urs-12-ene- and 28-norurs-12-ene- type conjugates with amino- and mercapto-1,3,4-oxadiazoles and mercapto-1,2,4-triazoles.

TL;DR: The novel hybrid heterocycles with amino and mercapto substituents possess a great potential for further derivatization and are prospective scaffolds for the synthesis of triterpenoid analogs with chemopreventive and cytotoxic properties.
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Synthesis and characterization of novel polyhalogenaromatic polyimide material for electro-optic applications

TL;DR: In this paper, a highly fluorinated aromatic polyimide based on 4-chloro-2,5,6-trifluoro-1,3-phenylenediamine and 2,2-bis(3′,4′-dicarboxyphenyl)hexafluoropropane dianhydride was prepared by two methods condensation in a solution followed by a high-temperature solid-state chain extension and one-pot high temperature polycondensation in benzoic acid melt.
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Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents.

TL;DR: The results indicate that the principal anti-inflammatory effect of hybrids is substantially provided with the triterpenoid scaffolds and in some cases with the azaprostanoid scaffold, but the latter makes a significant contribution to reducing the toxicity of hybrids.