T
Theresa Köbe
Researcher at McGill University
Publications - 34
Citations - 899
Theresa Köbe is an academic researcher from McGill University. The author has contributed to research in topics: Cognitive decline & Medicine. The author has an hindex of 15, co-authored 24 publications receiving 552 citations. Previous affiliations of Theresa Köbe include German Center for Neurodegenerative Diseases & Douglas Mental Health University Institute.
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Journal ArticleDOI
Combined omega-3 fatty acids, aerobic exercise and cognitive stimulation prevents decline in gray matter volume of the frontal, parietal and cingulate cortex in patients with mild cognitive impairment
Theresa Köbe,A. Veronica Witte,Ariane Schnelle,Anne Lesemann,Sonja Fabian,Valentina A. Tesky,Johannes Pantel,Agnes Flöel +7 more
TL;DR: Preliminary evidence is provided that omega-3 FA intake combined with aerobic exercise and cognitive stimulation prevents atrophy in AD-related brain regions in MCI patients, compared to omega- 3 FA intake plus the control condition of stretching and toning.
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Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline
Claudia Schwarz,Slaven Stekovic,Miranka Wirth,Gloria Benson,Philipp Royer,Stephan J. Sigrist,Thomas R. Pieber,Christopher Dammbrueck,Christoph Magnes,Tobias Eisenberg,Tobias Pendl,Jens Bohlken,Theresa Köbe,Frank Madeo,Agnes Flöel +14 more
TL;DR: The data demonstrate that sperMidine supplementation using a spermidine-rich plant extract is safe and well-tolerated in mice and older adults, and allow for longer-term intervention studies in humans to investigate the impact of sper midine treatment on cognition and brain integrity.
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The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial
Miranka Wirth,Gloria Benson,Claudia Schwarz,Theresa Köbe,Ulrike Grittner,Dietmar Schmitz,Stephan J. Sigrist,Stephan J. Sigrist,Jens Bohlken,Slaven Stekovic,Frank Madeo,Agnes Flöel +11 more
TL;DR: In this pilot trial, nutritional spermidine was associated with a positive impact on memory performance in older adults with subject cognitive decline, and the beneficial effect might be mediated by stimulation of neuromodulatory actions in the memory system.
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Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
Miranka Wirth,Claudia Schwarz,Gloria Benson,Nora Horn,Ralph Buchert,Catharina Lange,Theresa Köbe,Stefan Hetzer,Marta Maglione,Marta Maglione,Eva Michael,Eva Michael,Stefanie Märschenz,K Mai,K Mai,Ute A. Kopp,Dietmar Schmitz,Dietmar Schmitz,Ulrike Grittner,Stephan J. Sigrist,Stephan J. Sigrist,Stephan J. Sigrist,Slaven Stekovic,Frank Madeo,Agnes Flöel,Agnes Flöel +25 more
TL;DR: The SmartAge trial aims to provide evidence of the impact of spermidine supplementation on memory performance in older individuals with SCD, and identify possible neurophysiological mechanisms of action underlying the anticipated cognitive benefits.
Journal ArticleDOI
Impact of Resveratrol on Glucose Control, Hippocampal Structure and Connectivity, and Memory Performance in Patients with Mild Cognitive Impairment
Theresa Köbe,A. Veronica Witte,Ariane Schnelle,Valentina A. Tesky,Johannes Pantel,Jan Philipp Schuchardt,Andreas Hahn,Jens Bohlken,Ulrike Grittner,Agnes Flöel +9 more
TL;DR: This proof-of-concept study indicates for the first-time that resveratrol intake may reduce glycated hemoglobin A1c, preserves hippocampus volume, and improves hippocampus RSFC in at-risk patients for dementia.