T
Thierry Lambert
Researcher at Pasteur Institute
Publications - 36
Citations - 5102
Thierry Lambert is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Acinetobacter baumannii & Plasmid. The author has an hindex of 26, co-authored 33 publications receiving 4611 citations. Previous affiliations of Thierry Lambert include University of Paris-Sud.
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Resistance-Nodulation-Cell Division-Type Efflux Pump Involved in Aminoglycoside Resistance in Acinetobacter baumannii Strain BM4454
TL;DR: Insertional inactivation ofadeB in BM4454 showed that the corresponding protein was responsible for aminoglycoside resistance and was involved in the level of susceptibility to other drugs including fluoroquinolones, tetracyclines, chloramphenicol, erythromycin, trimethoprim, and ethidium bromide.
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Diversity of CTX‐M β‐lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals
Michèle Saladin,Van Cao,Thierry Lambert,Jean-Luc Donay,Jean-Louis Herrmann,Zahia Ould-Hocine,Charlotte Verdet,Françoise Delisle,Alain Philippon,Guillaume Arlet +9 more
TL;DR: Nine clinical isolates of Enterobacteriaceae isolated in three Parisian hospitals showed a particular extended-spectrum cephalosporin-resistance profile characterized by resistance to cefotaxime and aztreonam but not to ceftazidime, suggesting that this chromosomal enzyme is the progenitor of the CTX-M-2/5 cluster.
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Expression of the RND-Type Efflux Pump AdeABC in Acinetobacter baumannii Is Regulated by the AdeRS Two-Component System
TL;DR: The AdeABC pump of Acinetobacter baumannii BM4454, which confers resistance to various antibiotic classes including aminoglycosides, is composed of the AdeA, AdeB, and AdeC proteins as mentioned in this paper.
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Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation
TL;DR: It appears that posttranscriptional modification of 16S rRNA can confer high-level broad-range resistance to aminoglycosides in gram-negative human pathogens.
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AdeIJK, a Resistance-Nodulation-Cell Division Pump Effluxing Multiple Antibiotics in Acinetobacter baumannii
TL;DR: Determination of the antibiotic susceptibility of these strains and of BM4652 and BM4579, in which the adeIJK operon was provided in trans, indicated that the AdeIJk pump contributes to resistance to β-lactams, chloramphenicol, tetracycline, erythromycin, lincosamides, fluoroquinolones, fusidic acid, novobiocin, rifampin, trimeth