T
Thomas C. Knauss
Researcher at Case Western Reserve University
Publications - 21
Citations - 952
Thomas C. Knauss is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Transplantation & Sirolimus. The author has an hindex of 14, co-authored 21 publications receiving 930 citations. Previous affiliations of Thomas C. Knauss include University Hospitals of Cleveland.
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Journal ArticleDOI
Comparison of Sirolimus vs. Mycophenolate Mofetil on Surgical Complications and Wound Healing in Adult Kidney Transplantation
John F Valente,Donald E. Hricik,Kelly Weigel,David Seaman,Thomas C. Knauss,Christopher T. Siegel,Kenneth A. Bodziak,James A. Schulak +7 more
TL;DR: The use of sirolimus, tacrolimus and prednisone was associated with a greater incidence of lymphoceles, non‐lymphocele perinephric fluid collections and other consequences of poor wound healing, as compared to contemporary patients treated with MMF, tacrophenolate mofetil andprednisone.
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Phosphatidic acid modulates DNA synthesis, phospholipase C, and platelet-derived growth factor mRNAs in cultured mesangial cells. Role of protein kinase C
TL;DR: It is proposed that changes in endogenous phospholipids such as PA or phosphatidylserine may serve as common signaling pathway for a variety of growth factors.
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Comparative effects of sirolimus and mycophenolate mofetil on erythropoiesis in kidney transplant patients.
Joshua J. Augustine,Thomas C. Knauss,James A. Schulak,Kenneth A. Bodziak,Christopher T. Siegel,Donald E. Hricik +5 more
TL;DR: Anemia and erythrocytosis are common after kidney transplantation and the influence of sirolimus compared to mycophenolate mofetil (MMF) on post‐transplant erythropoiesis is investigated.
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Endothelin stimulates PDGF secretion in cultured human mesangial cells.
TL;DR: The role of endothelin in the release of another potent vasoconstrictor and mitogen of human mesangial cells, the platelet-derived growth factor, is investigated and data suggest a mechanism by whichendothelin may regulate mesangia cell function in disease states.
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Withdrawal of steroid therapy in African American kidney transplant recipients receiving sirolimus and tacrolimus.
Donald E. Hricik,Thomas C. Knauss,Kenneth A. Bodziak,Kelly Weigel,Victoria Rodriguez,David Seaman,Christopher T. Siegel,John F Valente,James A. Schulak +8 more
TL;DR: Use of sirolimus and tacrolimus, without the use of induction antibody therapy, allows withdrawal of prednisone as early as 3 months posttransplant with low rates of subsequent acute rejection in African American kidney transplant recipients.