Thomas Fischer

TL;DR: Genetic evidence is provided that Rap1b is involved in a common pathway of integrin activation, is required for normal hemostasis in vivo, and may be a clinically relevant antithrombotic therapy target.

TL;DR: To assess future drought losses, the regional gross domestic product under shared socioeconomic pathways instead of using a static socioeconomic scenario is predicted and increasing precipitation and evapotranspiration patterns are identified for the 1.5 °C and 2.0 °C global warming above the preindustrial at 2020–2039 and 2040–2059, respectively.

TL;DR: Data show that myocardial reperfusion injury can be inhibited by using proteasome inhibitors, which likely function through the inhibition of NF-kappaB activation.

TL;DR: In this paper, the spatial and temporal characteristics of precipitation trends in the Zhujiang River basin, South China, are analyzed, and nonparametric trend tests are applied to daily precipitation data from 192 weather stations between 1961 and 2007 for the following indices: annual, monthly, and daily precipitation; annual and monthly number of rain days and precipitation intensity.

TL;DR: In this paper, a five-model ensemble mean from CMIP6 was chosen to project drought characteristics in South Asia under the latest SSPs-RCPs emission scenarios (SSP1-26, SSP2-45, and SSP5-85) for the period 2020-2099.