T
Thomas Gaffney
Researcher at Research Triangle Park
Publications - 9
Citations - 4505
Thomas Gaffney is an academic researcher from Research Triangle Park. The author has contributed to research in topics: Gene & Systemic acquired resistance. The author has an hindex of 8, co-authored 9 publications receiving 4344 citations.
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Journal ArticleDOI
Requirement of Salicylic Acid for the Induction of Systemic Acquired Resistance
Thomas Gaffney,Leslie Friedrich,Bernard Vernooij,David Vincent Negrotto,Gordon Nye,Scott Uknes,Eric R. Ward,Helmut Kessmann,John Ryals +8 more
TL;DR: Salicylic acid is essential for the development of systemic acquired resistance in tobacco and was investigated in transgenic tobacco plants harboring a bacterial gene encoding salicylate hydroxylase.
Journal ArticleDOI
A Central Role of Salicylic Acid in Plant Disease Resistance
Terrence P. Delaney,Scott Uknes,Bernard Vernooij,Leslie Friedrich,Kris Weymann,David Vincent Negrotto,Thomas Gaffney,Manuela Gut-Rella,Helmut Kessmann,Eric R. Ward,John Ryals +10 more
TL;DR: Transgenic tobacco and Arabidopsis thaliana expressing the bacterial enzyme salicylate hydroxylase cannot accumulate salicylic acid, which makes the plants unable to induce systemic acquired resistance, but also leads to increased susceptibility to viral, fungal, and bacterial pathogens.
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The Ashbya gossypii Genome as a Tool for Mapping the Ancient Saccharomyces cerevisiae Genome
Fred S. Dietrich,Fred S. Dietrich,Sylvia Voegeli,Sophie Brachat,Anita Lerch,Krista Gates,Sabine Steiner,Christine Mohr,Rainer Pöhlmann,Philippe P. Luedi,Philippe P. Luedi,Sangdun Choi,Rod A. Wing,Albert Flavier,Thomas Gaffney,Peter Philippsen +15 more
TL;DR: The genome of the filamentous ascomycete Ashbya gossypii provided compelling evidence that the evolution of S. cerevisiae included a whole genome duplication orfusion of two related species and showed which of the duplicated genes lost one copy and which retained both copies.
Journal ArticleDOI
Global regulation of expression of antifungal factors by a Pseudomonas fluorescens biological control strain.
Thomas Gaffney,Stephen Lam,J. M. Ligon,Gates K,Frazelle A,Di Maio J,Hill S,Goodwin S,Torkewitz N,Allshouse Am +9 more
TL;DR: Genetic analysis indicated a gene homologous to response regulators of bacterial two-component systems was sufficient to complement the pleiotropic mutants and to activate antifungal genes in heterologous strains.
Journal ArticleDOI
Molecular analysis of genes encoding phenazine biosynthesis in the biological control bacterium Pseudomonas aureofaciens 30–84
TL;DR: Results indicate that phenazine biosynthesis in P. aureofaciens shares similarities with the shikimic acid, enterochelin, and tryptophan biosynthetic pathways.