S
Sangdun Choi
Researcher at Ajou University
Publications - 205
Citations - 9597
Sangdun Choi is an academic researcher from Ajou University. The author has contributed to research in topics: Toll-like receptor & Innate immune system. The author has an hindex of 46, co-authored 199 publications receiving 8102 citations. Previous affiliations of Sangdun Choi include Texas A&M University & California Institute of Technology.
Papers
More filters
Journal ArticleDOI
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.
TL;DR: These results provide an alternative strategy for eliciting RNAi-mediated target cleavage using low concentrations of synthetic RNA as substrates for cellular Dicer-mediated cleavage.
Journal ArticleDOI
The Ashbya gossypii Genome as a Tool for Mapping the Ancient Saccharomyces cerevisiae Genome
Fred S. Dietrich,Fred S. Dietrich,Sylvia Voegeli,Sophie Brachat,Anita Lerch,Krista Gates,Sabine Steiner,Christine Mohr,Rainer Pöhlmann,Philippe P. Luedi,Philippe P. Luedi,Sangdun Choi,Rod A. Wing,Albert Flavier,Thomas Gaffney,Peter Philippsen +15 more
TL;DR: The genome of the filamentous ascomycete Ashbya gossypii provided compelling evidence that the evolution of S. cerevisiae included a whole genome duplication orfusion of two related species and showed which of the duplicated genes lost one copy and which retained both copies.
Journal ArticleDOI
Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate beta-Catenin-dependent Gene Expression
TL;DR: This study provides several lines of evidence that the mouse Cristin/R-spondin family proteins function as Fzd8 and LRP6 receptor ligands and induce the canonical Wnt/β-catenin signaling pathway, leading to TCF-dependent gene activation.
Journal ArticleDOI
A Structure-Based Drug Discovery Paradigm.
TL;DR: This review focuses on the currently available methods and algorithms for structure-based drug design including virtual screening and de novo drug design, with a special emphasis on AI- and deep-learning-based methods used for drug discovery.
Journal ArticleDOI
Highly coordinated gene regulation in mouse skeletal muscle regeneration
Zhen Yan,Sangdun Choi,Xuebin Liu,Mei Zhang,Jeoffrey J. Schageman,Sun Young Lee,Rebecca Hart,Ling Lin,Frederick A. Thurmond,R. Sanders Williams +9 more
TL;DR: This study identifies novel genes potentially important for muscle regeneration and reveals highly coordinated myogenic cell proliferation and differentiation programs in adult skeletal muscle regeneration in vivo.