T
Thomas Harcke
Researcher at Johns Hopkins University
Publications - 1
Citations - 116
Thomas Harcke is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Loss of heterozygosity & Patched. The author has an hindex of 1, co-authored 1 publications receiving 106 citations.
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Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
Kimberly J. Briggs,Ian M. Corcoran-Schwartz,Wei Zhang,Thomas Harcke,Wendy Devereux,Stephen B. Baylin,Charles G. Eberhart,D. Neil Watkins +7 more
TL;DR: It is shown that Hic1 is a direct transcriptional repressor of Atonal Homolog 1 (Atoh1), a proneural transcription factor essential for cerebellar development, and that ATOH1 expression is required for human medulloblastoma cell growth in vitro.