T
Thomas Kosztowski
Researcher at Johns Hopkins University School of Medicine
Publications - 59
Citations - 1463
Thomas Kosztowski is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Lumbar & Hydrocephalus. The author has an hindex of 20, co-authored 59 publications receiving 1139 citations. Previous affiliations of Thomas Kosztowski include Johns Hopkins University & Brown University.
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Journal ArticleDOI
The biomechanics of pedicle screw augmentation with cement
Benjamin D. Elder,Sheng Fu L. Lo,Christina Holmes,Courtney Rory Goodwin,Thomas Kosztowski,Ioan A. Lina,John Locke,Timothy F. Witham +7 more
TL;DR: Polymethylmethacrylate and various calcium ceramics appear promising for the augmentation of pedicle screw fixation biomechanically in both osteoporosis and revision spine surgery models.
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Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target: Laboratory investigation
Wesley Hsu,Ahmed Mohyeldin,Sagar R. Shah,Colette M. Ap Rhys,Lakesha F. Johnson,Neda I. Sedora-Roman,Thomas Kosztowski,Ola Awad,Edward F. McCarthy,David M. Loeb,Jean Paul Wolinsky,Ziya L. Gokaslan,Alfredo Quinones-Hinojosa +12 more
TL;DR: It is demonstrated for the first time that silencing of Brachyury using short hairpin RNA renders the morphology of chordoma cells to a more differentiated-like state and leads to complete growth arrest and senescence with an inability to be passaged serially in vitro.
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Disparities in Access to Neuro-oncologic Care in the United States
Debraj Mukherjee,Hasan A. Zaidi,Thomas Kosztowski,Kaisorn L. Chaichana,Henry Brem,David C. Chang,Alfredo Quinones-Hinojosa +6 more
TL;DR: African Americans and Hispanics have disproportionately worse access to high-quality neuro-oncologic care over time compared with whites, implicating socioeconomic factors in predicting admission tohigh-quality centers.
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Use of S2-Alar-iliac Screws Associated With Less Complications Than Iliac Screws in Adult Lumbosacropelvic Fixation.
Benjamin D. Elder,Wataru Ishida,Sheng Fu L. Lo,Christina Holmes,C. Rory Goodwin,Thomas Kosztowski,Ali Bydon,Ziya L. Gokaslan,Jean Paul Wolinsky,Daniel M. Sciubba,Timothy F. Witham +10 more
TL;DR: The use of the S2AI technique over the IS technique was an independent predictor of preventing reoperation and SSI, while achieving similar clinical and functional outcomes.
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Applications of neural and mesenchymal stem cells in the treatment of gliomas.
TL;DR: This review introduces neural and mesenchymal stem cells, discusses the advances that have been made in the utilization of these stem cells as therapies and in diagnostic imaging, and concludes by addressing various challenges and concerns regarding these therapies.