T
Thomas N. Vilches
Researcher at Yale University
Publications - 47
Citations - 982
Thomas N. Vilches is an academic researcher from Yale University. The author has contributed to research in topics: Vaccination & Population. The author has an hindex of 8, co-authored 37 publications receiving 246 citations. Previous affiliations of Thomas N. Vilches include York University & State University of Campinas.
Papers
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Journal ArticleDOI
The impact of vaccination on COVID-19 outbreaks in the United States.
Seyed M. Moghadas,Thomas N. Vilches,Kevin Zhang,Chad R. Wells,Affan Shoukat,Burton H. Singer,Lauren Ancel Meyers,Kathleen M. Neuzil,Joanne M. Langley,Meagan C. Fitzpatrick,Alison P. Galvani +10 more
TL;DR: In this article, the authors evaluated the impact of a 2-dose COVID-19 vaccination campaign on reducing incidence, hospitalization, and deaths in the United States (US) by developing an agent-based model of SARS-CoV-2 transmission.
Posted ContentDOI
The impact of vaccination on COVID-19 outbreaks in the United States
Seyed M. Moghadas,Thomas N. Vilches,Kevin Zhang,Chad R. Wells,Affan Shoukat,Burton H. Singer,Lauren Ancel Meyers,Kathleen M. Neuzil,Joanne M. Langley,Meagan C. Fitzpatrick,Alison P. Galvani +10 more
TL;DR: The results indicate that vaccination can have a substantial impact on reducing disease transmission and adverse clinical outcomes, however, with uptake of 40% or less in the population, vaccination is unlikely to completely eliminate the need for non-pharmaceutical interventions.
Journal ArticleDOI
Evaluation of COVID-19 vaccination strategies with a delayed second dose.
Seyed M. Moghadas,Thomas N. Vilches,Kevin Zhang,Shokoofeh Nourbakhsh,Pratha Sah,Meagan C. Fitzpatrick,Meagan C. Fitzpatrick,Alison P. Galvani +7 more
TL;DR: In this article, the authors developed an agent-based model of COVID-19 transmission to compare the impact of these 2 vaccination strategies, while varying the temporal waning of vaccine efficacy following the first dose and the level of preexisting immunity in the population.
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Accelerated vaccine rollout is imperative to mitigate highly transmissible COVID-19 variants
Pratha Sah,Thomas N. Vilches,Seyed M. Moghadas,Meagan C. Fitzpatrick,Meagan C. Fitzpatrick,Burton H. Singer,Peter J. Hotez,Alison P. Galvani +7 more
TL;DR: In this article, the authors evaluated the impact of accelerated vaccine distribution on curbing the disease burden of novel SARS-CoV-2 variants by using an agent-based model of transmission and vaccination to simulate the spread of novel variants with S-Gene Target Failure (SGTF) in addition to the original strain.
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The impact of mask-wearing and shelter-in-place on COVID-19 outbreaks in the United States.
TL;DR: Mask-wearing, even with the use of non-medical masks with only 20% efficacy in preventing disease transmission, has a substantial impact on outbreak control, amid ongoing outbreaks.