T
Thomas Nägele
Researcher at University of Tübingen
Publications - 197
Citations - 6916
Thomas Nägele is an academic researcher from University of Tübingen. The author has contributed to research in topics: Magnetic resonance imaging & Diffusion MRI. The author has an hindex of 43, co-authored 181 publications receiving 6379 citations.
Papers
More filters
Journal ArticleDOI
High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial
Eckhard Thiel,Agnieszka Korfel,Peter Martus,Lothar Kanz,Frank Griesinger,Michael Rauch,Alexander Röth,Bernd Hertenstein,Theda von Toll,Thomas Hundsberger,H. Mergenthaler,Malte Leithäuser,Tobias Birnbaum,Lars Fischer,Kristoph Jahnke,Ulrich Herrlinger,Ludwig Plasswilm,Thomas Nägele,Torsten Pietsch,Michael Bamberg,Michael Weller,Michael Weller +21 more
TL;DR: The hypothesis was that the omission of whole brain radiotherapy does not compromise overall survival, with a non-inferiority margin of 0·9, and the primary hypothesis was not proven.
Journal ArticleDOI
PET/MRI: Paving the Way for the Next Generation of Clinical Multimodality Imaging Applications
TL;DR: Multimodality imaging and, more specifically, the combination of PET and CT has matured into an important diagnostic tool and requires not only significant modifications of the PET detector to make it compact and insensitive to magnetic fields but also a major redesign of the MRI hardware.
Journal ArticleDOI
Awareness of the Functioning of One's Own Limbs Mediated by the Insular Cortex?
TL;DR: The use of lesion mapping in 27 stroke patients is used to show that the right posterior insula is commonly damaged in patients with anosognosia for hemiplegia/hemiparesis but is significantly less involved in hemipLegic/hemIParetic patients without anos Cognosia, suggesting that the insular cortex is integral to self-awareness and to one's beliefs about the functioning of body parts.
Journal ArticleDOI
Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients
Wilhelm Küker,Thomas Nägele,Agnieska Korfel,Stefan Heckl,Eckhard Thiel,Michael Bamberg,Michael Weller,Ulrich Herrlinger +7 more
TL;DR: Pre-treatment MRI examinations of 100 immunologically competent patients with biopsy-proven PCNSL revealed a uniformly pathologic pattern of metabolite concentrations in all patients, and DW-MRI and proton spectroscopy may aid in differential diagnosis.
Journal ArticleDOI
Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*
Daniela Berg,Katherine Schweitzer,Petra Leitner,Alexander Zimprich,Peter Lichtner,Petra Belcredi,Theresa Brüssel,Claudia Schulte,Sylvia Maass,Thomas Nägele,Zbigniew K. Wszolek,Thomas Gasser +11 more
TL;DR: Late onset and typical l-dopa responsive parkinsonian features were generally observed, often accompanied by impairment of executive functions and high interference values in neuropsychological testing, as well as sleeping disturbances but rare hallucinations.