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Agnieszka Korfel
Researcher at Charité
Publications - 132
Citations - 4050
Agnieszka Korfel is an academic researcher from Charité. The author has contributed to research in topics: Primary central nervous system lymphoma & Ifosfamide. The author has an hindex of 35, co-authored 128 publications receiving 3599 citations.
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Journal ArticleDOI
High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial
Eckhard Thiel,Agnieszka Korfel,Peter Martus,Lothar Kanz,Frank Griesinger,Michael Rauch,Alexander Röth,Bernd Hertenstein,Theda von Toll,Thomas Hundsberger,H. Mergenthaler,Malte Leithäuser,Tobias Birnbaum,Lars Fischer,Kristoph Jahnke,Ulrich Herrlinger,Ludwig Plasswilm,Thomas Nägele,Torsten Pietsch,Michael Bamberg,Michael Weller,Michael Weller +21 more
TL;DR: The hypothesis was that the omission of whole brain radiotherapy does not compromise overall survival, with a non-inferiority margin of 0·9, and the primary hypothesis was not proven.
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Phase I Trial of the Trifunctional Anti-HER2 × Anti-CD3 Antibody Ertumaxomab in Metastatic Breast Cancer
Philipp Kiewe,Stephan Hasmüller,Steffen Kahlert,Maja Heinrigs,Brigitte Rack,Alexander Marmé,Agnieszka Korfel,Michael Jäger,Horst Lindhofer,Harald Sommer,Eckhard Thiel,Michael Untch +11 more
TL;DR: Treatment with triple infusions of ertumaxomab yields a strong immunologic response and measurements of cytokines suggest a strong T helper cell type 1–associated immune response.
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Surgery for primary CNS lymphoma? Challenging a paradigm
TL;DR: This analysis of the largest PCNSL trial ever performed challenges the traditional view that the extent of resection has no prognostic impact on this disease and proposes to reconsider the statement that efforts at resection should be discouraged.
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Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma
Martina Deckert,Andreas Engert,Wolfgang Brück,Andrés José Maria Ferreri,Jürgen Finke,Gerald Illerhaus,W Klapper,Agnieszka Korfel,Ralf Küppers,Mohammad Maarouf,Manuel Montesinos-Rongen,Werner Paulus,Uwe Schlegel,Hans Lassmann,Otmar D. Wiestler,Reiner Siebert,Lisa M. DeAngelis +16 more
TL;DR: This review combines the discussion of diagnosis, differential diagnosis and recent progress in studies addressing the molecular pathogenesis as well as therapeutic options in PCNSL.
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Relapse of primary central nervous system lymphoma : clinical features, outcome and prognostic factors
Kristoph Jahnke,Eckhard Thiel,Peter Martus,Ulrich Herrlinger,Michael Weller,Lars Fischer,Agnieszka Korfel +6 more
TL;DR: Survival of patients with relapsed PCNSL is poor despite high response rates to salvage therapy, and good KPS, isolated systemic relapse and treatment for relapse were significantly associated with longer survival.