Thomas P. Schmalzried

TL;DR: The concept of the effective joint space is suggested to include all periprosthetic regions that are accessible to joint fluid and thus accessible to particulate debris to indicate that joint fluid penetrates far more extensively than previously thought.

TL;DR: This study indicates that both the UCLA activity rating and the investigator visual analog scale are valid for routine activity assessment in a clinical setting.

TL;DR: Late aseptic loosening of cemented acetabular components is governed by the progressive, three-dimensional resorption of the bone immediately adjacent to the cement mantle, which is biologic in nature, not mechanical.

TL;DR: The microscopic morphology of worn polyethylene surfaces was compared with that of the associatedpolyethylene particles for acetabular cups tested in a wear simulator and for cups worn in vivo, suggesting that the same lubrication and wear processes were acting in the simulator as in vivo.

TL;DR: A method of tissue digestion using sodium hydroxide was applied to the isolation and recovery of ultra-high-molecular-weight polyethylene (UHMWPE) particles from tissues around failed total hip replacements to elucidate aspects of biomaterial particle size and shape that are important to the biologic response to, and clinical outcome of, total joint replacement.