T
Thomas R. Lynch
Researcher at University of Southampton
Publications - 133
Citations - 10520
Thomas R. Lynch is an academic researcher from University of Southampton. The author has contributed to research in topics: Dialectical behavior therapy & Borderline personality disorder. The author has an hindex of 44, co-authored 132 publications receiving 9702 citations. Previous affiliations of Thomas R. Lynch include University of Exeter & Kent State University.
Papers
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Journal ArticleDOI
Clinical Definition of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer
David M. Jackman,William Pao,Gregory J. Riely,Jeffrey A. Engelman,Mark G. Kris,Pasi A. Jänne,Thomas R. Lynch,Bruce E. Johnson,Vincent A. Miller +8 more
TL;DR: Criteria be used to define more precisely acquired resistance to EGFR TKIs and should minimize reporting of false-positive and false-negative activity in these clinical trials and would facilitate the identification of agents that truly overcome acquired Resistance to gefitinib and erlotinib.
Journal ArticleDOI
Efficacy of dialectical behavior therapy in women veterans with borderline personality disorder
Cedar R. Koons,Clive J. Robins,J. Lindsey Tweed,Thomas R. Lynch,Alicia Gonzalez,Jennifer Q. Morse,G. Kay Bishop,Marian I. Butterfield,Lori A. Bastian +8 more
TL;DR: In this paper, women veterans who met criteria for borderline personality disorder (BPD) were randomly assigned to Dialectical Behavior Therapy (DBT) or to treatment as usual (TAU) for 6 months.
Journal ArticleDOI
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma
Robert J. Soiffer,Thomas R. Lynch,Martin C. Mihm,Kenneth Jung,Catherine Rhuda,Jan C. Schmollinger,F S Hodi,L Liebster,P Lam,Steven J. Mentzer,Samuel Singer,Kenneth K. Tanabe,Cosimi Ab,Rosemary B. Duda,Arthur J. Sober,Atul K. Bhan,John F. Daley,Donna Neuberg,Gareth Parry,J Rokovich,L Richards,J Drayer,Anton Berns,Shirley M. Clift,Lawrence K. Cohen,Richard C. Mulligan,Glenn Dranoff +26 more
TL;DR: It is demonstrated that vaccination with irradiated autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor stimulates potent antitumor immunity in humans with metastatic melanoma.
Journal ArticleDOI
Dialectical Behavior Therapy for Borderline Personality Disorder
TL;DR: This paper provided a brief introduction to DBT, followed by a critical appraisal of empirical support for the treatment and a discussion of current research trends, and concluded that most of the specific concerns raised regarding DBT's early empirical base have been meaningfully addressed in subsequent randomized controlled trials.
Journal ArticleDOI
Mechanisms of change in dialectical behavior therapy: theoretical and empirical observations.
TL;DR: The primary purpose of this article is to address a variety of potential mechanisms of change that may be associated with those aspects of DBT that are unique to the treatment and its theoretical underpinnings.