T
Tiia J. Honkanen
Researcher at Oulu University Hospital
Publications - 3
Citations - 80
Tiia J. Honkanen is an academic researcher from Oulu University Hospital. The author has contributed to research in topics: Trastuzumab & Breast cancer. The author has an hindex of 3, co-authored 3 publications receiving 46 citations.
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Journal ArticleDOI
Prognostic and predictive role of tumour-associated macrophages in HER2 positive breast cancer.
Tiia J. Honkanen,Antti Tikkanen,Antti Tikkanen,Peeter Karihtala,Peeter Karihtala,Markus J. Mäkinen,Juha P. Väyrynen,Jussi Koivunen,Jussi Koivunen +8 more
TL;DR: High number of iNOS+ M1-like macrophages combined with high number of CD8+ T-cells in the CT was significantly associated with improved survival and predicted patient’s ability to remain progression-free without trastuzumab after responding to the therapy.
Journal ArticleDOI
Prognostic and predictive role of spatially positioned tumour infiltrating lymphocytes in metastatic HER2 positive breast cancer treated with trastuzumab.
Tiia J. Honkanen,Tiina Moilanen,Tiina Moilanen,Peeter Karihtala,Peeter Karihtala,Satu Tiainen,Päivi Auvinen,Juha P. Väyrynen,Markus J. Mäkinen,Markus J. Mäkinen,Jussi Koivunen,Jussi Koivunen +11 more
TL;DR: Important prognostic and predictive role of tumour infiltrating lymphocytes in center of the tumours in metastatic HER2+ breast cancer is suggested.
Journal ArticleDOI
HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC
TL;DR: It is suggested that HER2 has an important role in the regulation of the CSLC phenotype in ALK translocated lung cancers that is mainly orchestrated by HER2/HER3 heterodimers.