M
Markus J. Mäkinen
Researcher at University of Oulu
Publications - 92
Citations - 4779
Markus J. Mäkinen is an academic researcher from University of Oulu. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 33, co-authored 81 publications receiving 4345 citations. Previous affiliations of Markus J. Mäkinen include Oulu University Hospital.
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Journal ArticleDOI
Pituitary Adenoma Predisposition Caused by Germline Mutations in the AIP Gene
Outi Vierimaa,Marianthi Georgitsi,Rainer Lehtonen,Pia Vahteristo,Antti Kokko,Anniina Raitila,Karoliina Tuppurainen,Tapani Ebeling,Pasi I. Salmela,Ralf Paschke,Sadi Gundogdu,Ernesto De Menis,Markus J. Mäkinen,Virpi Launonen,Auli Karhu,Lauri A. Aaltonen +15 more
TL;DR: Combining chip-based technologies with genealogy data, germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene in individuals with pituitary adenoma predisposition (PAP) are identified.
Journal ArticleDOI
Inflammation and prognosis in colorectal cancer.
Kai Klintrup,Johanna M. Mäkinen,Saila Kauppila,Päivi Väre,Jukka Melkko,Hannu Tuominen,Karoliina Tuppurainen,Jyrki Mäkelä,Tuomo J. Karttunen,Markus J. Mäkinen +9 more
TL;DR: Inflammatory cell response at the invasive border is a relevant prognostic indicator and could be easily incorporated into the routine evaluation of histopathological specimens.
Journal ArticleDOI
Colorectal serrated adenocarcinoma.
TL;DR: Serrated adenocarcinoma is a recently described, distinct variant of CRC, characterized by early involvement of oncogenic BRAF mutations, excess CpG island methylation (CIM) and subsequent low‐ or high‐level DNA microsatellite instability (MSI).
Journal ArticleDOI
Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia.
Marianthi Georgitsi,Anniina Raitila,Auli Karhu,Rob B. van der Luijt,Cora M. Aalfs,Timo Sane,Outi Vierimaa,Markus J. Mäkinen,Karoliina Tuppurainen,Ralph Paschke,Oliver Gimm,Christian A. Koch,Sadi Gundogdu,Anneke Lucassen,Marc Tischkowitz,Louise Izatt,Simon Aylwin,Gul Bano,Shirley Hodgson,Ernesto De Menis,Virpi Launonen,Pia Vahteristo,Lauri A. Aaltonen +22 more
TL;DR: The results support the previous finding that germline CDKN1B/p27(Kip1) mutations predispose to a human MEN1-like condition.
Journal ArticleDOI
Colorectal carcinoma associated with serrated adenoma--prevalence, histological features, and prognosis.
Markus J. Mäkinen,Susannah M. C. George,Petra Jernvall,Jyrki Mäkelä,Pirkko Vihko,Tuomo J. Karttunen +5 more
TL;DR: It is concluded that carcinoma associated with serrated adenoma is a distinct type of colorectal neoplasm, accounting for 5.8% of all coloreCTal carcinoma cases in this study.