T
Timothy J. David
Researcher at University of Manchester
Publications - 134
Citations - 7415
Timothy J. David is an academic researcher from University of Manchester. The author has contributed to research in topics: Atopic dermatitis & Cystic fibrosis. The author has an hindex of 28, co-authored 133 publications receiving 7317 citations. Previous affiliations of Timothy J. David include Bristol Royal Infirmary & Boston Children's Hospital.
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Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease
TL;DR: SRL 172 was associated with an improvement in the severity of the dermatitis in children with moderate-to-severe disease, and it is concluded that reduced exposure to mycobacteria might ameliorate their disease.
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Effect of childhood eczema and asthma on parental sleep and well-being: a prospective comparative study.
TL;DR: The psychological impact of childhood atopic eczema on parents and carers is poorly quantified and the need for further research into this issue is unclear.
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Atopic dermatitis is associated with a low-producer transforming growth factor β1 cytokine genotype ☆
Peter D. Arkwright,Jennifer M. Chase,Sarah J. Babbage,Vera Pravica,Timothy J. David,Ian V. Hutchinson +5 more
TL;DR: TGFB1 genotype may partly explain the strong genetic predisposition to AD, which is associated with hyperresponsiveness of lymphocytes to allergens.
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Hypothalamic-pituitary-adrenal function and glucocorticoid sensitivity in atopic dermatitis.
TL;DR: Evidence of HPA suppression but lack of clinical response to GC treatment excluded significant generalized GC resistance, which would suggest that localized resistance to GCs within the diseased skin may be part of the aetiopathogenesis of severe AD.