Ting Li

TL;DR: It was found that a higher degree of social integration was associated with lower risk of physiological dysregulation in a dose–response manner in both early and later life, and lack of social connections was associatedWith vastly elevated risk in specific life stages.

TL;DR: Survival analyses are conducted and evidence is found that supports the mediation role of chronic inflammation in the link between social isolation and mortality and a high-risk fibrinogen level and cumulative inflammation burden may be particularly important in this link.

TL;DR: The results demonstrate that there are strong reciprocal associations between older adults' health conditions and network types, and programs designed to enhance healthy aging to focus on improving the bridging social capital of older adults so that they can break the vicious cycle between network isolation and poor health conditions.

TL;DR: A four-parameter model describing mortality as the first passage of an abstract measure of survival capacity, vitality, is developed and used to explore four classic problems in demography, demonstrating how the first-passage approach provides a unique and informative perspective into the processes that shape the survival curves of populations.

TL;DR: High social integration predicted significantly lower risks of both individual and overall metabolic dysregulation and suggested additional psychosocial and biological pathways to consider in future research on the contributions of social deficits to disease etiology and old-age mortality.