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Tom G Connell
Researcher at Royal Children's Hospital
Publications - 58
Citations - 1907
Tom G Connell is an academic researcher from Royal Children's Hospital. The author has contributed to research in topics: Tuberculosis & Tuberculin. The author has an hindex of 18, co-authored 56 publications receiving 1758 citations.
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Journal ArticleDOI
How reliable is a negative blood culture result? Volume of blood submitted for culture in routine practice in a children's hospital.
TL;DR: In routine clinical practice, a negative blood culture result is almost inevitable for a large proportion of blood cultures because of the submission of an inadequate volume of blood.
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Effect of HIV-1 Infection on T-Cell–based and Skin Test Detection of Tuberculosis Infection
Molebogeng X. Rangaka,Katalin A. Wilkinson,Ronnett Seldon,Gilles van Cutsem,Graeme Meintjes,Chelsea Morroni,Priscilla Mouton,Lavanya Diwakar,Tom G Connell,Gary Maartens,Robert J. Wilkinson +10 more
TL;DR: Significant differences in agreement between the tests and with the Mantoux test varied from poor to fair, highlighting the need for prospective studies to determine which test may predict the subsequent risk of tuberculosis.
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A three-way comparison of tuberculin skin testing, QuantiFERON-TB gold and T-SPOT.TB in children.
TL;DR: The correct interpretation of a negative assay in a child with a positive skin test in clinical practice remains challenging and highlights the need for longitudinal studies to determine the negative predictive value of IGRAs.
Journal ArticleDOI
Performance of a whole blood interferon gamma assay for detecting latent infection with Mycobacterium tuberculosis in children
Tom G Connell,Nigel Curtis,Nigel Curtis,Sarath Ranganathan,Sarath Ranganathan,Jim Buttery,Jim Buttery +6 more
TL;DR: The whole blood IFN-γ assay may have lower sensitivity than the TST in diagnosing TB infection in children, and a significant proportion of wholeBlood IFn-γ assays fail when used as a screening assay in routine practice.
Journal ArticleDOI
The influence of bacille Calmette-Guerin vaccine strain on the immune response against tuberculosis: a randomized trial.
Nicole Ritz,Binita Dutta,Susan Donath,Dan Casalaz,Tom G Connell,Marc Tebruegge,Roy M. Robins-Browne,Willem A. Hanekom,Warwick J. Britton,Nigel Curtis +9 more
TL;DR: There are significant differences in the immune response induced by different BCG vaccine strains in newborn infants, which have potentially important implications for global antituberculosis immunization policies and future tuberculosis vaccine trials.