G
Gary Maartens
Researcher at University of Cape Town
Publications - 414
Citations - 16983
Gary Maartens is an academic researcher from University of Cape Town. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 65, co-authored 354 publications receiving 14736 citations. Previous affiliations of Gary Maartens include Johns Hopkins University & Groote Schuur Hospital.
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Journal ArticleDOI
HIV infection: epidemiology, pathogenesis, treatment, and prevention
TL;DR: The role of immune activation in the pathogenesis of non-AIDS clinical events (major causes of morbidity and mortality in people on antiretroviral therapy) is receiving increased recognition and breakthroughs in the prevention of HIV important to public health include male medical circumcision.
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Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings.
Graeme Meintjes,Stephen D. Lawn,Stephen D. Lawn,Fabio Scano,Gary Maartens,Martyn A. French,William Worodria,Julian Elliott,David M Murdoch,Robert J. Wilkinson,Robert J. Wilkinson,Robert J. Wilkinson,Catherine Seyler,Laurence John,Maarten F. Schim van der Loeff,Peter Reiss,Lut Lynen,Edward N. Janoff,Charles F. Gilks,Robert Colebunders,Robert Colebunders +20 more
TL;DR: In this paper, consensus case definitions for paradoxical tuberculosis-associated IRIS, ART-associated tuberculosis, and unmasking tuberculosis associated IRIS were derived, which can be used by clinicians and researchers in a variety of settings to promote standardisation and comparability of data.
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Outcomes after two years of providing antiretroviral treatment in Khayelitsha South Africa.
David Coetzee,Katherine Hildebrand,Andrew Boulle,Gary Maartens,Francoise Louis,Veliswa Labatala,Hermann Reuter,Nonthutuzelo Ntwana,Eric Goemaere +8 more
TL;DR: ART can be provided in resource-limited settings with good patient retention and clinical outcomes and with responsible implementation, ART is a key component of a comprehensive response to the epidemic in those communities most affected by HIV.
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The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Keertan Dheda,Tawanda Gumbo,Gary Maartens,Kelly E. Dooley,Ruth McNerney,Megan Murray,Jennifer Furin,Edward A. Nardell,Leslie London,Erica Lessem,Grant Theron,Paul D. van Helden,Stefan Niemann,Matthias Merker,David W. Dowdy,Annelies Van Rie,Annelies Van Rie,Gilman Kit Hang Siu,Jotam G. Pasipanodya,Camilla Rodrigues,Taane G. Clark,F. A. Sirgel,Aliasgar Esmail,Hsien-Ho Lin,Sachin R Atre,H. Simon Schaaf,Kwok Chiu Chang,Christoph Lange,Payam Nahid,Zarir F Udwadia,C. Robert Horsburgh,Gavin J. Churchyard,Gavin J. Churchyard,Dick Menzies,Anneke C. Hesseling,Eric L. Nuermberger,Helen McIlleron,Kevin P. Fennelly,Eric Goemaere,Ernesto Jaramillo,Marcus Low,Carolina Morán Jara,Nesri Padayatchi,Robin M. Warren +43 more
TL;DR: Several lines of evidence suggest that alternative mechanisms-including pharmacokinetic variability, induction of efflux pumps that transport the drug out of cells, and suboptimal drug penetration into tuberculosis lesions-are likely crucial to the pathogenesis of drug-resistant tuberculosis.
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Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa.
Jean B. Nachega,Michael Hislop,Hoang Nguyen,David W. Dowdy,Richard E. Chaisson,Leon Regensberg,Mark F. Cotton,Gary Maartens +7 more
TL;DR: Compared with adults, adolescents in southern Africa are less adherent to ART and have lower rates of virology suppression and immunologic recovery and a higher rate of virologic rebound after initial suppression.