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Robert J. Wilkinson

Researcher at Francis Crick Institute

Publications -  484
Citations -  30974

Robert J. Wilkinson is an academic researcher from Francis Crick Institute. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 80, co-authored 433 publications receiving 26292 citations. Previous affiliations of Robert J. Wilkinson include Case Western Reserve University & Medical Research Council.

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An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

Matthew Berry, +24 more
- 19 Aug 2010 - 
TL;DR: A hitherto underappreciated role of type I IFN-αβ signalling in the pathogenesis of TB is demonstrated, which has implications for vaccine and therapeutic development and a broad range of transcriptional biomarkers with potential as diagnostic and prognostic tools to combat the TB epidemic are provided.
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The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

Clifton E. Barry, +11 more
- 26 Oct 2009 - 
TL;DR: The biology of latent tuberculosis is discussed as part of a broad range of responses that occur following infection with Mycobacterium tuberculosis, which result in the formation of physiologically distinct granulomatous lesions that provide microenvironments with differential ability to support or suppress the persistence of viable bacteria.
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The Immune Response in Tuberculosis

Anne O'Garra, +5 more
- 21 Mar 2013 - 
TL;DR: What the authors know about the immune response in tuberculosis, in human disease, and in a range of experimental models is summarized, all of which are essential to advancing the mechanistic knowledge base of the host-pathogen interactions that influence disease outcome.
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Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study

Robert J. Wilkinson, +9 more
- 19 Feb 2000 - 
TL;DR: In this article, the interaction between serum vitamin D (25-hydroxycholecalciferol) concentrations and VDR genotype on susceptibility to tuberculosis was investigated, and it was found that 25-hydroxcholeciferols deficiency was associated with active tuberculosis (odds ratio 2.9 [95% CI 1.3-6.5], p=0.008).
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Andrea Cossarizza, +462 more
- 01 Oct 2019 - 
TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.