T
Tomohiro Hayashi
Researcher at Kobe University
Publications - 34
Citations - 1157
Tomohiro Hayashi is an academic researcher from Kobe University. The author has contributed to research in topics: Heart failure & Natriuretic peptide. The author has an hindex of 12, co-authored 31 publications receiving 673 citations.
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Journal ArticleDOI
Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis.
Naofumi Yoshida,Takuo Emoto,Tomoya Yamashita,Hikaru Watanabe,Tomohiro Hayashi,Tokiko Tabata,Namiko Hoshi,Naoya Hatano,Genki Ozawa,Naoto Sasaki,Taiji Mizoguchi,Hilman Zulkifli Amin,Hilman Zulkifli Amin,Yushi Hirota,Wataru Ogawa,Takuji Yamada,Ken-ichi Hirata +16 more
TL;DR: The translational research findings identify a previously unknown link between specific gut bacteria and atherosclerosis, and may help prevent CAD.
Journal ArticleDOI
Analysis of Gut Microbiota in Coronary Artery Disease Patients: a Possible Link between Gut Microbiota and Coronary Artery Disease
Takuo Emoto,Tomoya Yamashita,Naoto Sasaki,Yushi Hirota,Tomohiro Hayashi,Anna So,Kazuyuki Kasahara,Keiko Yodoi,Takuya Matsumoto,Taiji Mizoguchi,Wataru Ogawa,Ken-ichi Hirata +11 more
TL;DR: It is demonstrated that the incidence of CAD was linked with an alteration of gut microbiota, and the CAD group was over-represented in enterotype "others" (III), compared with the Ctrl or HV group, although the possibility that some drugs affect the gut flora types is questioned.
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Characterization of gut microbiota profiles in coronary artery disease patients using data mining analysis of terminal restriction fragment length polymorphism: gut microbiota could be a diagnostic marker of coronary artery disease
Takuo Emoto,Tomoya Yamashita,Toshio Kobayashi,Naoto Sasaki,Yushi Hirota,Tomohiro Hayashi,Anna So,Kazuyuki Kasahara,Keiko Yodoi,Takuya Matsumoto,Taiji Mizoguchi,Wataru Ogawa,Ken-ichi Hirata +12 more
TL;DR: The possibility that gut microbiota is a diagnostic marker of suffering from CAD is demonstrated and operational taxonomic unit 853 (OTU853), OTU657, and OTU990 were determined important both by the data mining method and by the usual statistical comparison.
Journal ArticleDOI
Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis
Kazuyuki Kasahara,Kazuyuki Kasahara,Takeshi Tanoue,Tomoya Yamashita,Keiko Yodoi,Takuya Matsumoto,Takuo Emoto,Taiji Mizoguchi,Tomohiro Hayashi,Naoki Kitano,Naoto Sasaki,Koji Atarashi,Kenya Honda,Ken-ichi Hirata +13 more
TL;DR: The findings indicated that the gut microbiota affected both hypercholesterolemia and atherogenesis in mice, and caused a significant reduction in atherosclerotic lesion formation compared with Conv ApoE−/− mice.
Journal ArticleDOI
Gut Microbiome and Plasma Microbiome-Related Metabolites in Patients With Decompensated and Compensated Heart Failure
Tomohiro Hayashi,Tomoya Yamashita,Hikaru Watanabe,Kenjiro Kami,Naofumi Yoshida,Tokiko Tabata,Takuo Emoto,Naoto Sasaki,Taiji Mizoguchi,Yasuhiro Irino,Ryuji Toh,Masakazu Shinohara,Yuko Okada,Wataru Ogawa,Takuji Yamada,Ken-ichi Hirata +15 more
TL;DR: The results suggest that gut microbiome composition and microbiome-related metabolites are altered in HF patients.