J. Appl. Cryst.の発刊に際して

Introduced to the Market in the Last Decade (2001−2011) Jiang Wang,† María Sańchez-Rosello,́‡,§ Jose ́ Luis Aceña, Carlos del Pozo,‡ Alexander E. Sorochinsky, Santos Fustero,*,‡,§ Vadim A. Soloshonok,* and Hong Liu*,† †Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China ‡Department of Organic Chemistry, Faculty of Pharmacy, University of Valencia, Av. Vicente Andreś Estelleś, 46100 Burjassot, Valencia, Spain Laboratorio de Molećulas Orgańicas, Centro de Investigacioń Príncipe Felipe, C/ Eduardo Primo Yuf́era 3, 46012 Valencia, Spain Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizab́al 3, 20018 San Sebastian, Spain IKERBASQUE, Basque Foundation for Science, Alameda Urquijo, 36-5 Plaza Bizkaia, 48011 Bilbao, Spain Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Murmanska Street 1, 02660 Kyiv-94, Ukraine

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011).

Asymmetric enamine catalysis.

Recent Advances in Asymmetric Organocatalytic 1,4-Conjugate Additions

Catalytic C-C bond-forming multi-component cascade or domino reactions: pushing the boundaries of complexity in asymmetric organocatalysis.

3,3‘-Bimorpholine Derivatives as a New Class of Organocatalysts for Asymmetric Michael Addition

A complex derived from the enantiomeric bipiperidine and copper(II) acetate hydrate is an efficient catalyst for the enantioselective Henry reaction. The easy availability of both catalyst components, mild reaction conditions, high yield, and good to excellent enantioselectivity make the catalyst useful for everyday practice.

Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine

Organocatalytic asymmetric synthesis of 3-chlorooxindoles bearing adjacent quaternary-tertiary centers.

Asymmetric Baeyer-Villiger Oxidation of Cyclobutanones.

3-Chlorooxoindoles have emerged as versatile precursors in the synthesis of spirocyclopropyl oxindoles. High enantio- and diastereoselectivity was attained under conditions of both iminium/enamine and H-bonding catalysis.

Tõnis Kanger

Papers

3,3‘-Bimorpholine Derivatives as a New Class of Organocatalysts for Asymmetric Michael Addition

Enantioselective Henry Reaction Catalyzed by CuII Salt and Bipiperidine

Organocatalytic asymmetric synthesis of 3-chlorooxindoles bearing adjacent quaternary-tertiary centers.

Asymmetric Baeyer-Villiger Oxidation of Cyclobutanones.

3-Chlorooxindoles: versatile starting materials for asymmetric organocatalytic synthesis of spirooxindoles