T
Toru Fujinaga
Researcher at Hokkaido University
Publications - 111
Citations - 4871
Toru Fujinaga is an academic researcher from Hokkaido University. The author has contributed to research in topics: Cartilage & Cardiac output. The author has an hindex of 29, co-authored 111 publications receiving 4614 citations. Previous affiliations of Toru Fujinaga include Osaka University & Japan Racing Association.
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Topical formulations and wound healing applications of chitosan.
TL;DR: Chitosan enhances the functions of inflammatory cells such as polymorphonuclear leukocytes (PMN), phagocytosis, production of osteopontin and leukotriene B4, macrophages, and fibroblasts, which promotes granulation and organization, therefore chitosans is beneficial for the large open wounds of animals.
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Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells (MSCs) in different hydrogels: Influence of collagen type II extracellular matrix on MSC chondrogenesis
Darko Bosnakovski,Morimichi Mizuno,Gonhyung Kim,Satoshi Takagi,Masahiro Okumura,Toru Fujinaga +5 more
TL;DR: It is demonstrated that collagen type II alone has the potential to induce and maintain MSC chondrogenesis, and prior interaction with TGF β1 to enhance the differentiation.
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Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs.
Hiroshi Ueno,Haruo Yamada,Ichiro Tanaka,Naoki Kaba,Mitsunobu Matsuura,Masahiro Okumura,Tsuyoshi Kadosawa,Toru Fujinaga +7 more
TL;DR: Results suggest chitosan to be having a function in the acceleration of infiltration of PMN cells at the early stage of wound healing, followed by the production of collagen by fibroblasts.
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Effects of chitin and its derivatives on the proliferation and cytokine production of fibroblasts in vitro
Takashi Mori,Masahiro Okumura,Mitsunobu Matsuura,Keisuke Ueno,Seiichi Tokura,Yoshiharu Okamoto,Sabro Minami,Toru Fujinaga +7 more
TL;DR: In vivo findings of a angiogenesis and migration of neutrophils may be due to persistent release of IL-8 from fibroblasts, supporting the notion that cell proliferation is accelerated indirectly by chitin and its derivatives when these materials are used in vivo.
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Isolation and multilineage differentiation of bovine bone marrow mesenchymal stem cells
Darko Bosnakovski,Morimichi Mizuno,Gonhyung Kim,Satoshi Takagi,Masahiro Okumura,Toru Fujinaga +5 more
TL;DR: It is demonstrated that cells harvested from bovine bone marrow are capable of in vitro extensive multiplication and multilineage differentiation, making them a relevant and invaluable model in the field of stem cell research.