T
Torunn Pedersen
Researcher at University Hospital of North Norway
Publications - 16
Citations - 417
Torunn Pedersen is an academic researcher from University Hospital of North Norway. The author has contributed to research in topics: Enterococcus faecium & Plasmid. The author has an hindex of 7, co-authored 13 publications receiving 318 citations.
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Journal ArticleDOI
PCR-based plasmid typing in Enterococcus faecium strains reveals widely distributed pRE25-, pRUM-, pIP501- and pHTβ-related replicons associated with glycopeptide resistance and stabilizing toxin–antitoxin systems
Torill C.S. Rosvoll,Torunn Pedersen,Hege Sletvold,Pål Jarle Johnsen,Johanna U. Ericson Sollid,Gunnar Skov Simonsen,Gunnar Skov Simonsen,Gunnar Skov Simonsen,Lars Bogø Jensen,Kaare Magne Nielsen,Arnfinn Sundsfjord,Arnfinn Sundsfjord +11 more
TL;DR: PCR-based replicon typing, linked to the detection of other important plasmid-encoded traits, seems to be a feasible tool for tracing disseminating resistance plasmids stably maintained in various environments.
Journal ArticleDOI
Investigating the mobilome in clinically important lineages of Enterococcus faecium and Enterococcus faecalis
Theresa Mikalsen,Torunn Pedersen,Rob J. L. Willems,Teresa M. Coque,Guido Werner,Eva Sadowy,Willem van Schaik,Lars Bogø Jensen,Arnfinn Sundsfjord,Kristin Hegstad +9 more
TL;DR: An overall high correlation was observed between the presence and absence of genes coding for resistance towards antibiotics, metals, biocides and their corresponding MGEs as well as their phenotypic antimicrobial susceptibility pattern.
Journal ArticleDOI
Spread of Plasmid-Encoded NDM-1 and GES-5 Carbapenemases among Extensively Drug-Resistant and Pandrug-Resistant Clinical Enterobacteriaceae in Durban, South Africa.
Torunn Pedersen,John Osei Sekyere,Usha Govinden,Krishnee Moodley,Audun Sivertsen,Ørjan Samuelsen,Ørjan Samuelsen,Sabiha Y. Essack,Arnfinn Sundsfjord,Arnfinn Sundsfjord +9 more
TL;DR: The findings imply independent plasmid acquisition followed by local dissemination of NDM-1-encoding plasmids in extensively drug-resistant and pandrug-resistant Enterobacteriaceae organisms isolated from in-patients in 10 private hospitals in Durban, South Africa.
Journal ArticleDOI
Increased high-level gentamicin resistance in invasive Enterococcus faecium is associated with aac(6')Ie-aph(2″)Ia-encoding transferable megaplasmids hosted by major hospital-adapted lineages.
Torill C.S. Rosvoll,Belinda L. Lindstad,Tracy Tamara Munthali Lunde,Kristin Hegstad,Kristin Hegstad,Bettina Aasnæs,Anette M. Hammerum,Camilla H. Lester,Gunnar Skov Simonsen,Gunnar Skov Simonsen,Arnfinn Sundsfjord,Arnfinn Sundsfjord,Torunn Pedersen +12 more
TL;DR: The increased prevalence of HLGR in invasive E. faecium in Norway is associated with hospital-adapted genetic lineages carrying aac(6')-Ie-aph(2″)-Ia-encoding transferable megaplasmids of the pLG1 replicon type.
Journal ArticleDOI
Silenced vanA gene cluster on a transferable plasmid cause outbreak of vancomycin variable enterococci
Audun Sivertsen,Torunn Pedersen,Kjersti Wik Larssen,Kåre Bergh,Torunn Gresdal Rønning,Andreas Radtke,Kristin Hegstad +6 more
TL;DR: An outbreak of vancomycin-variable vanA+ enterococci (VVE) able to escape phenotypic detection by current guidelines is reported and the molecular mechanisms for in vivo switching into vancomYcin resistance and horizontal spread of the vanA cluster are demonstrated.