Toshiaki Hasegawa

TL;DR: The requirement for Odf2 in basal foot formation is revealed, revealing a crucial role of this structure in the polarized alignment of basal bodies and coordinated ciliary beating.

TL;DR: It is found that spherical silica particles could form a micellar structure in water in the presence of an organic solution of a toluene/polystyrene mixture and was evidenced by formation of golf-ball-like polystyrene particles with dimples imprinting morphologies of the hydrophobic part of modifiedsilica particles.

TL;DR: It is proposed that cellular projections can enable long-range interaction between membrane-bound ligands and their receptors, and can substitute for the effect of a diffusible factor that would be expected by the conventional reaction-diffusion (Turing) model.

TL;DR: Using AAV2/5 in photoreceptor cells, the possibility of gene replacement for the developmental disorder and subsequent degeneration of retinal photoreceptors caused by the absence of Crx is demonstrated and the usefulness of AAV-mediated gene transfer into the P0 mouse retina is confirmed.

TL;DR: The ultra-HVEM with an accelerating voltage of 3 MV at Osaka University is capable of achieving excellent penetration and resolution for thick specimens as mentioned in this paper, which makes it an invaluable extension of 3D observation by electron tomography.