T
Toshihiro Fujioka
Researcher at Fukuoka University
Publications - 129
Citations - 3534
Toshihiro Fujioka is an academic researcher from Fukuoka University. The author has contributed to research in topics: Triterpene & Sodium hydride. The author has an hindex of 29, co-authored 127 publications receiving 3261 citations. Previous affiliations of Toshihiro Fujioka include Fukuyama University & Nagasaki University.
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Journal ArticleDOI
Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.
Toshihiro Fujioka,Yoshiki Kashiwada,Robert E. Kilkuskie,L. M. Cosentino,Lawrence M. Ballas,Jack B. Jiang,William P. Janzen,Ih-Sheng Chen,Kuo Hsiung Lee +8 more
TL;DR: Evaluation of anti-HIV activity with eight derivatives of 1 revealed that dihydrobetulinic acid was also a potent inhibitor of HIV replication, and there was no apparent correlation between anti-hIV activity and the inhibition of PKC among these compounds.
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Anti-HIV benzylisoquinoline alkaloids and flavonoids from the leaves of Nelumbo nucifera, and structure-activity correlations with related alkaloids.
Yoshiki Kashiwada,Akihiro Aoshima,Yasumasa Ikeshiro,Yuh Pan Chen,Hiroshi Furukawa,Masataka Itoigawa,Toshihiro Fujioka,Kunihide Mihashi,L. Mark Cosentino,Susan L. Morris-Natschke,Kuo Hsiung Lee +10 more
TL;DR: Compounds 1, 3, 12, and 14-16 can serve as new leads for further development of anti-AIDS agents as well as other benzylisoquinoline, aporphine, and bisbenzylisoquoline alkaloids, which were previously isolated from the leaves and embryo of Nelumbo nucifera and evaluated for anti-HIV activity.
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Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.
Yoshiki Kashiwada,Wang Hk,Tsuneatsu Nagao,S Kitanaka,Ichiro Yasuda,Toshihiro Fujioka,Takashi Yamagishi,L. M. Cosentino,Mutsuo Kozuka,H Okabe,Yasumasa Ikeshiro,Chang Qi Hu,E Yeh,Kuo Hsiung Lee +13 more
TL;DR: Oleanolic acid was identified as an anti-HIV principle from several plants, including Rosa woodsii, Prosopis glandulosa, Phoradendron juniperinum, Syzygium claviflorum, and Hyptis capitata, and Ternstromia gymnanthera.
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Isolation of rhododaurichromanic acid B and the anti-HIV principles rhododaurichromanic acid A and rhododaurichromenic acid from Rhododendron dauricum
Yoshiki Kashiwada,Kimihisa Yamazaki,Yasumasa Ikeshiro,Takashi Yamagishi,Toshihiro Fujioka,Kunihide Mihashi,Koichi Mizuki,L. Mark Cosentino,Keith R. Fowke,Susan L. Morris-Natschke,Kuo Hsiung Lee +10 more
TL;DR: In this paper, two novel chromane derivatives and the known chromene were isolated from the leaves and twigs of Rhodo-dendron dauricum, and the absolute stereostructures of 1 and 2 were established by spectroscopic examination and X-ray crystallographic analysis.
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Antiproliferative constituents from umbelliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from the root of Angelica japonica
Toshihiro Fujioka,Kazuhiro Furumi,Hiroko Fujii,Hikaru Okabe,Kunihide Mihashi,Yukitaka Nakano,Hisashi Matsunaga,Mitsuo Katano,Masato Mori +8 more
TL;DR: The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth and a new furanocoumarin named japoangelone and four furanOCoumarins ethers of falcarindiol were isolated.