T
Toyohiro Sato
Researcher at Nagoya City University
Publications - 9
Citations - 81
Toyohiro Sato is an academic researcher from Nagoya City University. The author has contributed to research in topics: Cholinergic & Hippocampus. The author has an hindex of 4, co-authored 7 publications receiving 58 citations.
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Journal ArticleDOI
Pleiotrophin promotes functional recovery after neural transplantation in rats.
TL;DR: It is revealed that pleiotrophin had effects on donor cells in neural transplantation in vivo and was additive to that of glial-cell line-derived neutropic factor.
Journal ArticleDOI
Enhancement of long-term potentiation via muscarinic modulation in the hippocampus of HCNP precursor transgenic mice
Yoshiaki Ohi,Daisuke Kato,Masayuki Mizuno,Toyohiro Sato,Yoshino Ueki,Cesario V. Borlongan,Kosei Ojika,Akira Haji,Noriyuki Matsukawa +8 more
TL;DR: Results suggest that muscarinic (M1) modulation of glutamatergic postsynaptic function may be involved in strengthening LTP in HCNP-pp Tg mice.
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Hippocampal Cholinergic Neurostimulating Peptide as a Possible Modulating Factor against Glutamatergic Neuronal Disability by Amyloid Oligomers.
Toyohiro Sato,Yoshiaki Ohi,Daisuke Kato,Masayuki Mizuno,Hiroshi Takase,Tetsuko Kanamori,Cesar V. Borlongan,Akira Haji,Noriyuki Matsukawa +8 more
TL;DR: Using hippocampal sections from mice, it is demonstrated that the cholinergic neural activation from the medial septal nucleus (MSN) enhanced the glutamatergic neuronal activity during unsaturated LTP but not during saturated LTP, suggesting that the persistingCholinergic activation might be a potential explanation for the individual differences in cognitive effects of AD pathological changes.
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Anatomical Links between White Matter Hyperintensity and Medial Temporal Atrophy Reveal Impairment of Executive Functions.
Takehiko Yamanaka,Yuto Uchida,Keita Sakurai,Daisuke Kato,Masayuki Mizuno,Toyohiro Sato,Yuta Madokoro,Yuko Kondo,Ayuko Suzuki,Yoshino Ueki,Fumiyasu Ishii,Cesar V. Borlongan,Noriyuki Matsukawa +12 more
TL;DR: Regression analysis revealed that MTA was the strongest predictor of flexibility and verbal fluency, which provides new insight into the relationship between quantitative MRI analyses and various types of executive dysfunction in elderly people with MCI due to AD and/or early phase AD.
Journal ArticleDOI
Reduced Cholinergic Activity in the Hippocampus of Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein Knockout Mice.
Yuta Madokoro,Yuta Yoshino,Daisuke Kato,Toyohiro Sato,Masayuki Mizuno,Tetsuko Kanamori,Masamitsu Shimazawa,Hideki Hida,Hideaki Hara,Mari Yoshida,Cesario V. Borlongan,Kosei Ojika,Noriyuki Matsukawa +12 more
TL;DR: This study demonstrates that HCNP may be a cholinergic regulator in the septo-hippocampal network and generates HCNP-pp knockout mice and assesses their cholineacetyltransferase-positive axons, local field potentials in CA1, and behavioral phenotypes.