Statistics for Spatial Data.

Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described. Methods In this retrospective, multicentre cohort study, we included all adult inpatients (≥18 years old) with laboratory-confirmed COVID-19 from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) who had been discharged or had died by Jan 31, 2020. Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. We used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death. Findings 191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03–1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61–12·23; p Interpretation The potential risk factors of older age, high SOFA score, and d-dimer greater than 1 μg/mL could help clinicians to identify patients with poor prognosis at an early stage. Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future. Funding Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences; National Science Grant for Distinguished Young Scholars; National Key Research and Development Program of China; The Beijing Science and Technology Project; and Major Projects of National Science and Technology on New Drug Creation and Development.

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

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Mitigation and Adaptation Strategies for Global Change

Terrestrial net primary production (NPP) quantifies the amount of atmospheric carbon fixed by plants and accumulated as biomass. Previous studies have shown that climate constraints were relaxing with increasing temperature and solar radiation, allowing an upward trend in NPP from 1982 through 1999. The past decade (2000 to 2009) has been the warmest since instrumental measurements began, which could imply continued increases in NPP; however, our estimates suggest a reduction in the global NPP of 0.55 petagrams of carbon. Large-scale droughts have reduced regional NPP, and a drying trend in the Southern Hemisphere has decreased NPP in that area, counteracting the increased NPP over the Northern Hemisphere. A continued decline in NPP would not only weaken the terrestrial carbon sink, but it would also intensify future competition between food demand and proposed biofuel production.

Drought-Induced Reduction in Global Terrestrial Net Primary Production from 2000 Through 2009

The State of Food and Agriculture

Hot spots are typically locations of abundant phenomena. In ecology, hot spots are often detected with a spatially global threshold, where a value for a given observation is compared with all values in a data set. When spatial relationships are important, spatially local definitions - those that compare the value for a given observation with locations in the vicinity, or the neighbourhood of the observation - provide a more explicit consideration of space. Here we outline spatial methods for hot spot detection: kernel estimation and local measures of spatial autocorrelation. To demonstrate these approaches, hot spots are detected in landscape level data on the magnitude of mountain pine beetle infestations. Using kernel estimators, we explore how selection of the neighbourhood size (τ) and hot spot threshold impact hot spot detection. We found that as T increases, hot spots are larger and fewer; as the hot spot threshold increases, hot spots become larger and more plentiful and hot spots will reflect coarser scale spatial processes. The impact of spatial neighbourhood definitions on the delineation of hot spots identified with local measures of spatial autocorrelation was also investigated. In general, the larger the spatial neighbourhood used for analysis, the larger the area, or greater the number of areas, identified as hot spots.

Detecting spatial hot spots in landscape ecology

Automated tree recognition in old growth conifer stands with high resolution digital imagery

http://web.pdx.edu/~nauna/articles/goward_2008.pdf

Estimation of insect infestation dynamics using a temporal sequence of Landsat data

The collection, visualization, and analysis of movement data is at the forefront of geographic information science research. Movement data are generally collected by recording an object's spatial location e.g., XY coordinates at discrete time intervals. Methods for extracting useful information, for example space–time patterns, from these increasingly large and detailed datasets have lagged behind the technology for generating them. In this article we review existing quantitative methods for analyzing movement data. The objective of this article is to provide a synthesis of the existing literature on quantitative analysis of movement data while identifying those techniques that have merit with novel datasets. Seven classes of methods are identified: 1 time geography, 2 path descriptors, 3 similarity indices, 4 pattern and cluster methods, 5 individual–group dynamics, 6 spatial field methods, and 7 spatial range methods. Challenges routinely faced in quantitative analysis of movement data include difficulties with handling space and time attributes together, representing time in GIS, and using classical statistical testing procedures with space–time movement data. Areas for future research include investigating equivalent distance comparisons in space and time, measuring interactions between moving objects, developing predictive frameworks for movement data, integrating movement data with existing geographic layers, and incorporating theory from time geography into movement models. In conclusion, quantitative analysis of movement data is an active research area with tremendous opportunity for new developments and methods.

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A review of quantitative methods for movement data

Science and reporting information needs for monitoring dynamics in land cover over time have prompted research, and made operational, a wide variety of change detection methods utilizing multiple dates of remotely sensed data. Change detection procedures based upon spectral values are common; however, landscape pattern analysis approaches which utilize spatial information inherent within imagery present opportunities for the generation of unique and ecologically important information. While the use of two images may provide the means to identify change, the use of more than two images for long-term monitoring affords the ability to identify a greater range of processes of landscape change, including rates and dynamics. The main objective of this review is to investigate and summarize the methods and applications of land cover spatial pattern analysis using three or more image dates. The potential and the limitations of landscape pattern indices are identified and discussed to inform application recommenda...

Trisalyn A. Nelson

Papers

Detecting spatial hot spots in landscape ecology

Automated tree recognition in old growth conifer stands with high resolution digital imagery

Estimation of insect infestation dynamics using a temporal sequence of Landsat data

A review of quantitative methods for movement data

Multitemporal remote sensing of landscape dynamics and pattern change: Describing natural and anthropogenic trends