T
Tsutomu Kasugai
Researcher at Osaka University
Publications - 100
Citations - 5527
Tsutomu Kasugai is an academic researcher from Osaka University. The author has contributed to research in topics: Breast cancer & Mast cell. The author has an hindex of 36, co-authored 99 publications receiving 5413 citations. Previous affiliations of Tsutomu Kasugai include Kyoto Prefectural University of Medicine.
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Age-dependent amelioration of hypoplastic anemia in Ws/Ws rats with a small deletion at the kinase domain of c-kit.
Masahiro Morimoto,Tsutomu Kasugai,Hideki Tei,Tomoko Jippo-Kanemoto,Yuzuru Kanakura,Yukihiko Kitamura +5 more
TL;DR: The white-spotting (Ws) locus of rats represents a 12-base deletion of the c-kit receptor tyrosine kinase, and the increase in morphologically identifiable erythroid precursors in the marrow of Ws/Ws rats was attributed to the increased concentration of colony-forming unit-erytroid (CFU-E).
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Malignant seeding of the lumpectomy cavity upon breast-conserving surgery.
Kazuyoshi Motomura,Hiroki Koyama,Shinzaburo Noguchi,Hideo Inaji,Tsutomu Kasugai,Sachiko Nagumo +5 more
TL;DR: Multivariate analysis revealed that the highest relative risk factor for positive cytology was evidence of cutting across cancer lesions, and the positivity was significantly higher in patients with an extensive intraductal component and less than or equal to 50 years of age.
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Breast-conserving treatment after neoadjuvant chemotherapy in large breast cancer.
Hideo Inaji,Yoshifumi Komoike,Kazuyoshi Motomura,Tsutomu Kasugai,Yuka Sawai,Masahiko Koizumi,Takayuki Nose,Hiroki Koyama +7 more
TL;DR: Long term follow-up is required to establish whether this procedure is a safe alternative to mastectomy for patients with large breast cancers, and the local recurrence rate appears to be comparable to that after BCT for early stage breast cancers.
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Effect of Tamoxifen on pS2 Expression in Human Breast Cancers
TL;DR: In this paper, the pS2 protein expression was found to be inhibited by tamoxifen (TAM) in 22 patients treated preoperatively with TAM and in 45 without TAM treatment (control group).
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The Possible Prognostic Significance of p53 Immunostaining Status of the Primary Tumor in Patients Developing Local Recurrence after Breast-Conserving Surgery
Shinzaburo Noguchi,Hiroki Koyama,Tsutomu Kasugai,Naoko Tsuji,Hitoshi Tsuda,Futoshi Akiyama,Kazuyoshi Motomura,Hideo Inaji +7 more
TL;DR: Only the p53 immunostaining status of the primary tumor was found to be a significant prognostic indicator for distant metastases; distant disease-free survival at 5 years after the local recurrence was 92% for patients with p53-negative cancers and 51% for those with p 53-positive cancers.