U
Una D. McCann
Researcher at Johns Hopkins University School of Medicine
Publications - 153
Citations - 12831
Una D. McCann is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: MDMA & Neurotoxicity. The author has an hindex of 56, co-authored 152 publications receiving 11926 citations. Previous affiliations of Una D. McCann include United States Department of the Army & Duke University.
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Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance.
TL;DR: When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences, and the ability to occasion such experiences prospectively will allow rigorous scientific investigations of their causes and consequences.
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Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings
TL;DR: Direct evidence of a decrease in a structural component of brain 5-HT neurons in human MDMA users is shown, which is directly linked with the extent of previous MDMA use.
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Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428
Una D. McCann,Dean F. Wong,Fuji Yokoi,Victor L. Villemagne,Robert F. Dannals,George A. Ricaurte +5 more
TL;DR: Persistent reductions in DAT density in methamphetamine and methcathinone users are suggestive of loss of DAT or loss of DA terminals and raise the possibility that as these individuals age, they may be at increased risk for the development of parkinsonism or neuropsychiatric conditions in which brain DA neurons have been implicated.
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Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later
TL;DR: When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences that, at 14-month follow-up, were considered by volunteers to be among the most personally meaningful and spiritually significant of their lives.
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Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects
Roland R. Griffiths,Matthew W. Johnson,William A. Richards,Brian D Richards,Una D. McCann,Robert Jesse +5 more
TL;DR: Under supportive conditions, 20 and 30 mg/70 kg psilocybin occasioned mystical-type experiences having persisting positive effects on attitudes, mood, and behavior.