Showing papers by "V. K. Unnikrishnan published in 2020"
TL;DR: The results clearly demonstrate the potential of echelle-based LIBS-Raman system in applications where more detailed information on complex samples like minerals, archaeological artifacts etc, is required with minimum sample damage or consumption.
24 citations
30 Jun 2020
TL;DR: The potential of optical spectroscopy based techniques for regular screening and early diagnosis of “Killer” diseases (various types of cancers, cardiovascular diseases, etc.) is discussed with focus on routine use under low-resource settings.
Abstract: In this paper the potential of optical spectroscopy based techniques for regular screening and early diagnosis of “Killer” diseases (various types of cancers, cardiovascular diseases, etc.) is discussed with focus on routine use under low-resource settings. A brief account of work carried out in our laboratory to design, assemble and optimize Laser Induced Fluorescence (LIF) based optical devices for routine screening, early diagnosis and discrimination of premalignant/malignant conditions in oral and other cancers is presented. An ultra-sensitive protein profiling system based on highly efficient High Performance Liquid Chromatograpy-Ultrasensitive Laser Induced Fluorescence (HPLC-LIF) detection, and its extensive use in monitoring various cancers, coronary conditions, gynecological problems etc. through protein profile pattern analyses of markers in body fluids is also discussed.
7 citations
21 Oct 2020
3 citations
TL;DR: Results of experiments on strand breakages induced by thermalized particles produced upon plasma-induced photolysis of water, and their inhibition, suggest implications beyond studies of DNA; they open new vistas for utilizing simple nanosecond lasers to explore the effect of ultra-low energy radiation on living matter under physiologically-relevant conditions.
Abstract: Electrons and •OH-radicals have been generated by using low-energy laser pulses of 6 ns duration (1064 nm wavelength) to create plasma in a suspension of plasmid DNA (pUC19) in water. Upon thermali...
2 citations