V
Valery F. Thompson
Researcher at University of Arizona
Publications - 41
Citations - 5711
Valery F. Thompson is an academic researcher from University of Arizona. The author has contributed to research in topics: Calpain & Calpastatin. The author has an hindex of 21, co-authored 39 publications receiving 5401 citations.
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Journal ArticleDOI
The Calpain System
TL;DR: How calpain activity is regulated in cells is still unclear, but the calpains ostensibly participate in a variety of cellular processes including remodeling of cytoskeletal/membrane attachments, different signal transduction pathways, and apoptosis.
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Is Z-disk degradation responsible for postmortem tenderization?
TL;DR: Electron microscope studies described in this paper show that, during the first 3 or 4 d of postmortem storage at 4 degrees C, both costameres and N2 lines are degraded.
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Role of the calpain system in muscle growth
TL;DR: Activity of the calpains in living cells is regulated by calpastatin and Ca2+, but the nature of this regulation is still unclear.
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Is calpain activity regulated by membranes and autolysis or by calcium and calpastatin
TL;DR: Although the Ca2+‐dependent proteinase (calpain) system has been found in every vertebrate cell that has been examined for its presence and has been detected in Drosophila and parasites, the physiological function(s) of this system remains unclear.
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Myofibrillar protein turnover: The proteasome and the calpains
TL;DR: It seems that both the calpains and the proteasome are responsible for myofibrillar protein turnover, but the mechanism is still unknown.