V
Vandana Gupta
Researcher at University of Delhi
Publications - 97
Citations - 3273
Vandana Gupta is an academic researcher from University of Delhi. The author has contributed to research in topics: Zebrafish & Skeletal muscle. The author has an hindex of 27, co-authored 88 publications receiving 2563 citations. Previous affiliations of Vandana Gupta include Johns Hopkins University & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Alkaliphilic bacteria: applications in industrial biotechnology
Indira P. Sarethy,Yashi Saxena,Aditi Kapoor,Manisha Sharma,Sanjeev Sharma,Vandana Gupta,Sanjay Gupta +6 more
TL;DR: An insight is provided into the huge diversity of alkaliphilic bacteria, the varied products obtained from them, and the need for further investigations on these interesting bacteria.
Journal ArticleDOI
Kelch proteins: emerging roles in skeletal muscle development and diseases.
Vandana Gupta,Alan H. Beggs +1 more
TL;DR: The Kelch superfamily is one of the largest evolutionary conserved gene families and many Kelch proteins function as substrate-specific adaptors for Cullin E3 ubiquitin ligase (Cul3), a core component of the ubiquit in-proteasome system to regulate the protein turnover.
Journal ArticleDOI
A Splice Site Mutation in Laminin-α2 Results in a Severe Muscular Dystrophy and Growth Abnormalities in Zebrafish
Vandana Gupta,Genri Kawahara,Jennifer Myers,Aye T. Chen,Thomas E. Hall,Chiara Manzini,Peter D. Currie,Yi Zhou,Leonard I. Zon,Leonard I. Zon,Louis M. Kunkel,Alan H. Beggs +11 more
TL;DR: This laminin-α2 deficient mutant fish represents a novel disease model to develop therapies for modulating splicing defects in congenital muscular dystrophies and to restore the muscle function in human patients with CMD.
Journal ArticleDOI
The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies
Vandana Gupta,Genri Kawahara,Stacey R. Gundry,Stacey R. Gundry,Aye T. Chen,Wayne I. Lencer,Yi Zhou,Leonard I. Zon,Leonard I. Zon,Louis M. Kunkel,Alan H. Beggs +10 more
TL;DR: In a forward genetic approach to identify novel genes for congenital muscle diseases, a zebrafish mutant, designated patchytail, was identified that exhibits degenerating muscle fibers with impaired motility behavior that is highly reminiscent of the phenotypes observed in the human conditions muscle-eye-brain disease and Walker-Warburg syndrome.
Book ChapterDOI
Phytochemicals as Antiviral Agents: Recent Updates
TL;DR: This chapter will emphasize on the reported phytochemicals and their derivatives, having antiviral properties and their mechanism to treat viral diseases.