V
Vandana Gupta
Researcher at University of Delhi
Publications - 97
Citations - 3273
Vandana Gupta is an academic researcher from University of Delhi. The author has contributed to research in topics: Zebrafish & Skeletal muscle. The author has an hindex of 27, co-authored 88 publications receiving 2563 citations. Previous affiliations of Vandana Gupta include Johns Hopkins University & Brigham and Women's Hospital.
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Journal ArticleDOI
α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms
TL;DR: Functional differences in vivo between sarcomeric isoforms are identified, providing functional evidence that the primary sequences of α‐actinin‐2 and α‐Actin in‐2 evolved differences to optimize their functions.
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Travel time to health facilities in areas of outbreak potential: maps for guiding local preparedness and response
E. N. Hulland,Kirsten E. Wiens,Shreya Shirude,Julia D. Morgan,Amelia Bertozzi-Villa,Tamer H. Farag,Nancy Fullman,Moritz U. G. Kraemer,Molly K. Miller-Petrie,Vandana Gupta,Robert C. Reiner,Robert C. Reiner,Peter M. Rabinowitz,Judith N. Wasserheit,Brent Bell,Simon I. Hay,Simon I. Hay,Daniel J. Weiss,David M. Pigott,David M. Pigott +19 more
TL;DR: These maps demonstrate the use of geospatial analytics for subnational preparedness, identifying facilities close to at-risk populations for prioritizing readiness to detect, treat, and respond to cases and highlighting where gaps in health facility accessibility exist.
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Modeling cyber-physical attacks based on stochastic game and Markov processes
K.C. Lalropuia,Vandana Gupta +1 more
TL;DR: A zero − sum stochastic game model is proposed to capture the system dynamics resulting from the attacker − defender interactions in an attacked CPS and the best strategies for counteracting the malicious activities are determined.
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Mullerian Inhibiting Substance Promotes Interferon γ-induced Gene Expression and Apoptosis in Breast Cancer Cells *
Yasunori Hoshiya,Vandana Gupta,Hirofumi Kawakubo,Elena F. Brachtel,Jennifer L. Carey,Laura M. Sasur,Andrew D Scott,Patricia K. Donahoe,Shyamala Maheswaran +8 more
TL;DR: It is demonstrated that in addition to interferons and cytokines, members of the TGFβ superfamily such as Mullerian inhibiting substance (MIS) and activin A also regulate IRF-1 expression, demonstrating a functional interaction between these two classes of signaling molecules in regulation of breast cancer cell growth.
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Mullerian inhibiting substance suppresses tumor growth in the C3(1)T antigen transgenic mouse mammary carcinoma model
Vandana Gupta,Jennifer L. Carey,Hirofumi Kawakubo,Alona Muzikansky,Jeffrey Green,Patricia K. Donahoe,David T. MacLaughlin,Shyamala Maheswaran +7 more
TL;DR: The results suggest that MIS can suppress the growth of mammary tumors in vivo, and suggest that the use of MIS to treat breast cancer should be extended.