Vanessa L. Peachee

TL;DR: Treatment with DEHP, DINP, DIHP, and BBP did not result in significant elevations in total serum IgE, IL-4, or IL-13, and it is unlikely that these substances would produce antibody-mediated respiratory allergy.

TL;DR: The effects on the primary IgM immune response in the B6C3F1 mice, thePrimary immunotoxicological rodents used by National Toxicology Program, and in the Sprague–Dawley rat, the primary rodent models used by industry are addressed.

TL;DR: Administration of a monoclonal antibody against mouse TNFα during pregnancy and lactation had little or no effect on selected immune parameters in mice, with only a possible minor attenuation of spleen cell response to immunization noted in the female F1 generation at 11 weeks of age.

TL;DR: The results from this study demonstrated that exposure to WDDD and EDDD produced minimal changes in the activities of B cells and natural killer cells, macrophages and neutrophils, and hematological parameters were not affected.

TL;DR: Results demonstrate that Thd immunomodulation altered host resistance to B16F10 and L. monocytogenes; and selective modulation of Thd on the immune system may be responsible for the pathogen or tumor-specific effect of this compound.