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Vasco Galhardo

Researcher at University of Porto

Publications -  41
Citations -  1705

Vasco Galhardo is an academic researcher from University of Porto. The author has contributed to research in topics: Chronic pain & Neuropathic pain. The author has an hindex of 17, co-authored 37 publications receiving 1477 citations. Previous affiliations of Vasco Galhardo include Institute of Business & Medical Careers & Instituto de Biologia Molecular e Celular.

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Forebrain pain mechanisms.

TL;DR: Results of clinical studies in neuropathic pain patients suggest that neuroimaging may help determine mechanisms of altered brain functions in pain as well as monitor the effects of pharmacologic interventions to optimize treatment in individual patients.
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Cognitive Impairment in Pain through Amygdala-Driven Prefrontal Cortical Deactivation

TL;DR: This study shows that the amygdala contributes not only to emotional-affective but also cognitive effects of pain, which has important implications for the understanding of amygdala functions and amygdalo-cortical interactions.
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Rodent versions of the iowa gambling task: opportunities and challenges for the understanding of decision-making.

TL;DR: New rodent models based on the same principle have been developed to investigate the neurobiological mechanisms underlying IGT-like decision-making on behavioral, neural, and pharmacological levels, and the comparative strengths, as well as the similarities and differences between these paradigms are discussed.
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Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain

TL;DR: The first report of the effect of chronic pain in rat decision-making processes is reported and supports the notion that pain may have profound effects on the functioning of the reward-aversion circuitry relevant to strategic planning.
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Impaired spatial memory performance in a rat model of neuropathic pain is associated with reduced hippocampus-prefrontal cortex connectivity.

TL;DR: The results show that the nerve lesion caused an impairment of working memory performance that is temporally associated with changes in the mPFC populational firing activity patterns when the animals navigated between decision points—when memory retention was most needed.